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Chapter 22.7, Problem 16P
Interpretation Introduction

a)

Student Value Bundle: Organic Chemistry, + OWLv2 with Student Solutions Manual eBook, 4 terms (24 months) Printed Access Card (NEW!!), Chapter 22.7, Problem 16P , additional homework tip  1

Interpretation:

Using an alkylation reaction as the key step how the compound shown can be prepared is to be given.

Concept introduction:

An alkylation reaction is used to introduce a methyl or a primary alkyl group in α- position of a ketone, ester or nitrile by a SN2 reaction of the enolate ion with an alkyl halide. Thus by looking at α- carbon of the product, the alkyl halide to be used in the reaction can be identified. The enolate ion can be produced by using lithium diisopropylamide (LDA).

To give:

Using an alkylation reaction as the key step how to prepare the compound shown.

Interpretation Introduction

b)

Student Value Bundle: Organic Chemistry, + OWLv2 with Student Solutions Manual eBook, 4 terms (24 months) Printed Access Card (NEW!!), Chapter 22.7, Problem 16P , additional homework tip  2

Interpretation:

Using an alkylation reaction as the key step how the compound shown can be prepared.

Concept introduction:

An alkylation reaction is used to introduce a methyl or a primary alkyl group in α- position of a ketone, ester or nitrile by a SN2 reaction of the enolate ion with an alkyl halide. Thus by looking at α- carbon of the product the alkyl halide to be used in the reaction can be identified. The enolate ion can be produced by using lithium diisopropylamide (LDA).

To give:

Using an alkylation reaction as the key step how to prepare the compound shown.

Interpretation Introduction

c)

Student Value Bundle: Organic Chemistry, + OWLv2 with Student Solutions Manual eBook, 4 terms (24 months) Printed Access Card (NEW!!), Chapter 22.7, Problem 16P , additional homework tip  3

Interpretation:

Using an alkylation reaction as the key step how the compound shown can be prepared.

Concept introduction:

An alkylation reaction is used to introduce a methyl or a primary alkyl group in α- position of a ketone, ester or nitrile by aSN2reaction of the enolate ion with an alkyl halide. Thus by looking at α- carbon of the product the alkyl halide to be used in the reaction can be identified. The enolate ion can be produced by using lithium diisopropylamide (LDA).

To give:

Using an alkylation reaction as the key step how to prepare the compound shown.

Interpretation Introduction

d)

Student Value Bundle: Organic Chemistry, + OWLv2 with Student Solutions Manual eBook, 4 terms (24 months) Printed Access Card (NEW!!), Chapter 22.7, Problem 16P , additional homework tip  4

Interpretation:

Using an alkylation reaction as the key step how the compound shown can be prepared.

Concept introduction:

An alkylation reaction is used to introduce a methyl or a primary alkyl group in α- position of a ketone, ester or nitrile by a SN2 reaction of the enolate ion with an alkyl halide. Thus by looking at α- carbon of the product the alkyl halide to be used in the reaction can be identified. The enolate ion can be produced by using lithium diisopropylamide (LDA).

To give:

Using an alkylation reaction as the key step how to prepare the compound shown.

Interpretation Introduction

e)

Student Value Bundle: Organic Chemistry, + OWLv2 with Student Solutions Manual eBook, 4 terms (24 months) Printed Access Card (NEW!!), Chapter 22.7, Problem 16P , additional homework tip  5

Interpretation:

Using an alkylation reaction as the key step how the compound shown can be prepared.

Concept introduction:

An alkylation reaction is used to introduce a methyl or a primary alkyl group in α- position of a ketone, ester or nitrile by a SN2 reaction of the enolate ion with an alkyl halide. Thus by looking at α- carbon of the product the alkyl halide to be used in the reaction can be identified. The enolate ion can be produced by using lithium diisopropylamide (LDA).

To give:

Using an alkylation reaction as the key step how to prepare the compound shown.

Interpretation Introduction

f)

Student Value Bundle: Organic Chemistry, + OWLv2 with Student Solutions Manual eBook, 4 terms (24 months) Printed Access Card (NEW!!), Chapter 22.7, Problem 16P , additional homework tip  6

Interpretation:

Using an alkylation reaction as the key step how the compound shown can be prepared.

Concept introduction:

An alkylation reaction is used to introduce a methyl or a primary alkyl group in α- position of a ketone, ester or nitrile by a SN2 reaction of the enolate ion with an alkyl halide. Thus by looking at α- carbon of the product the alkyl halide to be used in the reaction can be identified. The enolate ion can be produced by using lithium diisopropylamide (LDA).

To give:

Using an alkylation reaction as the key step how to prepare the compound shown.

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Please correct answer and don't used hand raiting
(11pts total) Consider the arrows pointing at three different carbon-carbon bonds in the molecule depicted below. Bond B Bond A Bond C a. (2pts) Which bond between A-C is weakest? Which is strongest? Place answers in appropriate boxes. Weakest Bond Strongest Bond b. (4pts) Consider the relative stability of all cleavage products that form when bonds A, B, AND C are homolytically cleaved/broken. Hint: cleavage products of bonds A, B, and C are all carbon radicals. i. Which ONE cleavage product is the most stable? A condensed or bond line representation is fine. ii. Which ONE cleavage product is the least stable? A condensed or bond line representation is fine. c. (5pts) Use principles discussed in lecture, supported by relevant structures, to succinctly explain the why your part b (i) radical is more stable than your part b(ii) radical. Written explanation can be no more than one-two succinct sentence(s)!

Chapter 22 Solutions

Student Value Bundle: Organic Chemistry, + OWLv2 with Student Solutions Manual eBook, 4 terms (24 months) Printed Access Card (NEW!!)

Ch. 22.7 - Draw a resonance structure of the acetonitrile...Ch. 22.7 - Why do you suppose ketone halogenations in acidic...Ch. 22.7 - Prob. 13PCh. 22.7 - Prob. 14PCh. 22.7 - Prob. 15PCh. 22.7 - Prob. 16PCh. 22.SE - Prob. 17VCCh. 22.SE - Prob. 18VCCh. 22.SE - Prob. 19VCCh. 22.SE - Prob. 20MPCh. 22.SE - Predict the product(s) and provide the mechanism...Ch. 22.SE - Predict the product(s) and provide the mechanism...Ch. 22.SE - Prob. 23MPCh. 22.SE - In the Hell–Volhard–Zelinskii reaction, only a...Ch. 22.SE - Prob. 25MPCh. 22.SE - Nonconjugated , -unsaturated ketones, such as...Ch. 22.SE - Prob. 27MPCh. 22.SE - Using curved arrows, propose a mechanism for the...Ch. 22.SE - Prob. 29MPCh. 22.SE - One of the later steps in glucose biosynthesis is...Ch. 22.SE - The Favorskii reaction involves treatment of an...Ch. 22.SE - Treatment of a cyclic ketone with diazomethane is...Ch. 22.SE - Prob. 33MPCh. 22.SE - Amino acids can be prepared by reaction of alkyl...Ch. 22.SE - Amino acids can also be prepared by a two-step...Ch. 22.SE - Heating carvone with aqueous sulfuric acid...Ch. 22.SE - Identify all the acidic hydrogens (pKa 25) in the...Ch. 22.SE - Rank the following compounds in order of...Ch. 22.SE - Prob. 39APCh. 22.SE - Base treatment of the following , -unsaturated...Ch. 22.SE - Prob. 41APCh. 22.SE - Prob. 42APCh. 22.SE - Prob. 43APCh. 22.SE - Which, if any, of the following compounds can be...Ch. 22.SE - Prob. 45APCh. 22.SE - Prob. 46APCh. 22.SE - Prob. 47APCh. 22.SE - How might you convert geraniol into either ethyl...Ch. 22.SE - Prob. 49APCh. 22.SE - One way to determine the number of acidic...Ch. 22.SE - Prob. 51APCh. 22.SE - Prob. 52APCh. 22.SE - Prob. 53APCh. 22.SE - Prob. 54APCh. 22.SE - Prob. 55APCh. 22.SE - Prob. 56APCh. 22.SE - All attempts to isolate primary and secondary...Ch. 22.SE - How would you synthesize the following compounds...Ch. 22.SE - Prob. 59APCh. 22.SE - Prob. 60APCh. 22.SE - Prob. 61APCh. 22.SE - Prob. 62APCh. 22.SE - As far back as the 16th century, South American...Ch. 22.SE - The key step in a reported laboratory synthesis of...Ch. 22.SE - Prob. 65AP
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