The mechanism of cleavage of 3-ketoacyl CoA by CoA should be determined. Concept introduction: Thiolase is an enzyme which converts two molecules of acetyl CoA into acetoacetyl CoA in the mevalonate pathway. This enzyme is also termed as acetyl-coenzyme A acetyltransferases. Thiolase plays an important role in various biosynthetic pathways, including beta-oxidation of fatty acids.

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Chapter 22, Problem 46P

Interpretation Introduction

Interpretation:

The mechanism of cleavage of 3-ketoacyl CoA by CoA should be determined.

Concept introduction:

Thiolase is an enzyme which converts two molecules of acetyl CoA into acetoacetyl CoA in the mevalonate pathway. This enzyme is also termed as acetyl-coenzyme A acetyltransferases. Thiolase plays an important role in various biosynthetic pathways, including beta-oxidation of fatty acids.

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