HUMAN PHYSIOLOGY: AN INTEG ACCESS C
HUMAN PHYSIOLOGY: AN INTEG ACCESS C
8th Edition
ISBN: 9780134714837
Author: Silverthorn
Publisher: PEARSON
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Chapter 22, Problem 30RQ

One of the debates in fluid therapy for diabetic ketoacidosis (DKA) is whether to administer bicarbonate (bicarb). Although it is generally accepted that bicarb should be given if the patient’s blood pH is <7.1 (life-threatening), most authorities do not give bicarb otherwise. One reason for not administering bicarb relates to the oxygen-binding capacity of hemoglobin. In DKA, patients have low levels of 2,3-BPG [p. 573]. When acidosis is corrected rapidly, 2,3-BPG is much slower to recover and may take 24 or more hours to return to normal.

Draw and label a graph of the normal oxygen-dissociation curve [p. 573]. Briefly explain and draw lines on the same graph to show:

  1. (a) what happens to oxygen release during DKA as a result of acidosis and low 2,3-BPG levels.
  2. (b) what happens to oxygen release when the metabolic acidosis is rapidly corrected with bicarbonate.
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After you feel comfortable with your counting method and identifying cells in the various stages of mitosis, use the four images below of whitefish blastula to count the cells in each stage until you reach 100 total cells, recording your data below in Data Table 1. (You may not need to use all four images. Stop counting when you reach 100 total cells.) After totaling the cells in each stage, calculate the percent of cells in each stage. (Divide total of stage by overall total of 100 and then multiply by 100 to obtain percentage.)   Data Table 1Stage    Totals    PercentInterphase        Mitosis:        Prophase        Metaphase        Anaphase        Telophase        Cytokinesis        Totals    100    100% To find the length of time whitefish blastula cells spend in each stage, multiply the percent (recorded as a decimal, in other words take the percent number and divide by 100) by 24 hours. (Example: If percent is 20%, then Time in Hours = .2 * 24 = 4.8) Record your data in Data…

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HUMAN PHYSIOLOGY: AN INTEG ACCESS C

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