Whether ErK signaling positively regulate Notum gene expression. The role of noncanonical Wnt signaling pathways in planarian regeneration. Introduction: The head-versus-tail regeneration decision in planarians, known as regeneration polarity, is a model for studying appropriate regeneration program specification. Wnt signaling controls regeneration polarity, with pathway components β-catenin-1 and wnt1 required to prevent head regeneration and promote tail regeneration at posterior-facing wounds. Wnt1 expression is upregulated near both anterior- and posterior-facing wounds. Notum (RNAi) animals regenerate an anterior-facing tail instead of a head, and double-RNAi experiments indicate notum inhibits Wnt signaling to promote head regeneration. notum expression is itself controlled by Wnt signaling, suggesting regulation of feedback inhibition controls the binary head-tail regeneration outcome.

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Chapter 22, Problem 2DQ

Summary Introduction

To review:

Whether ErK signaling positively regulate Notum gene expression. The role of noncanonical Wnt signaling pathways in planarian regeneration.

Introduction:

The head-versus-tail regeneration decision in planarians, known as regeneration polarity, is a model for studying appropriate regeneration program specification. Wnt signaling controls regeneration polarity, with pathway components β-catenin-1 and wnt1 required to prevent head regeneration and promote tail regeneration at posterior-facing wounds. Wnt1 expression is upregulated near both anterior- and posterior-facing wounds. Notum (RNAi) animals regenerate an anterior-facing tail instead of a head, and double-RNAi experiments indicate notum inhibits Wnt signaling to promote head regeneration. notum expression is itself controlled by Wnt signaling, suggesting regulation of feedback inhibition controls the binary head-tail regeneration outcome.

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Question

Chapter 22, Problem 2DQ

Summary Introduction

To review:

Whether ErK signaling positively regulate Notum gene expression. The role of noncanonical Wnt signaling pathways in planarian regeneration.

Introduction:

The head-versus-tail regeneration decision in planarians, known as regeneration polarity, is a model for studying appropriate regeneration program specification. Wnt signaling controls regeneration polarity, with pathway components β-catenin-1 and wnt1 required to prevent head regeneration and promote tail regeneration at posterior-facing wounds. Wnt1 expression is upregulated near both anterior- and posterior-facing wounds. Notum (RNAi) animals regenerate an anterior-facing tail instead of a head, and double-RNAi experiments indicate notum inhibits Wnt signaling to promote head regeneration. notum expression is itself controlled by Wnt signaling, suggesting regulation of feedback inhibition controls the binary head-tail regeneration outcome.

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Answer 3

Question

Chapter 22, Problem 2DQ

Summary Introduction

To review:

Whether ErK signaling positively regulate Notum gene expression. The role of noncanonical Wnt signaling pathways in planarian regeneration.

Introduction:

The head-versus-tail regeneration decision in planarians, known as regeneration polarity, is a model for studying appropriate regeneration program specification. Wnt signaling controls regeneration polarity, with pathway components β-catenin-1 and wnt1 required to prevent head regeneration and promote tail regeneration at posterior-facing wounds. Wnt1 expression is upregulated near both anterior- and posterior-facing wounds. Notum (RNAi) animals regenerate an anterior-facing tail instead of a head, and double-RNAi experiments indicate notum inhibits Wnt signaling to promote head regeneration. notum expression is itself controlled by Wnt signaling, suggesting regulation of feedback inhibition controls the binary head-tail regeneration outcome.

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Answer 4

Question

Chapter 22, Problem 2DQ

Summary Introduction

To review:

Whether ErK signaling positively regulate Notum gene expression. The role of noncanonical Wnt signaling pathways in planarian regeneration.

Introduction:

The head-versus-tail regeneration decision in planarians, known as regeneration polarity, is a model for studying appropriate regeneration program specification. Wnt signaling controls regeneration polarity, with pathway components β-catenin-1 and wnt1 required to prevent head regeneration and promote tail regeneration at posterior-facing wounds. Wnt1 expression is upregulated near both anterior- and posterior-facing wounds. Notum (RNAi) animals regenerate an anterior-facing tail instead of a head, and double-RNAi experiments indicate notum inhibits Wnt signaling to promote head regeneration. notum expression is itself controlled by Wnt signaling, suggesting regulation of feedback inhibition controls the binary head-tail regeneration outcome.

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Answer 5

Chapter 22, Problem 2DQ

Summary Introduction

To review:

Whether ErK signaling positively regulate Notum gene expression. The role of noncanonical Wnt signaling pathways in planarian regeneration.

Introduction:

The head-versus-tail regeneration decision in planarians, known as regeneration polarity, is a model for studying appropriate regeneration program specification. Wnt signaling controls regeneration polarity, with pathway components β-catenin-1 and wnt1 required to prevent head regeneration and promote tail regeneration at posterior-facing wounds. Wnt1 expression is upregulated near both anterior- and posterior-facing wounds. Notum (RNAi) animals regenerate an anterior-facing tail instead of a head, and double-RNAi experiments indicate notum inhibits Wnt signaling to promote head regeneration. notum expression is itself controlled by Wnt signaling, suggesting regulation of feedback inhibition controls the binary head-tail regeneration outcome.

Answer 6

Chapter 22, Problem 2DQ

Summary Introduction

To review:

Whether ErK signaling positively regulate Notum gene expression. The role of noncanonical Wnt signaling pathways in planarian regeneration.

Introduction:

The head-versus-tail regeneration decision in planarians, known as regeneration polarity, is a model for studying appropriate regeneration program specification. Wnt signaling controls regeneration polarity, with pathway components β-catenin-1 and wnt1 required to prevent head regeneration and promote tail regeneration at posterior-facing wounds. Wnt1 expression is upregulated near both anterior- and posterior-facing wounds. Notum (RNAi) animals regenerate an anterior-facing tail instead of a head, and double-RNAi experiments indicate notum inhibits Wnt signaling to promote head regeneration. notum expression is itself controlled by Wnt signaling, suggesting regulation of feedback inhibition controls the binary head-tail regeneration outcome.

Answer 7

Chapter 22, Problem 2DQ

Summary Introduction

To review:

Whether ErK signaling positively regulate Notum gene expression. The role of noncanonical Wnt signaling pathways in planarian regeneration.

Introduction:

The head-versus-tail regeneration decision in planarians, known as regeneration polarity, is a model for studying appropriate regeneration program specification. Wnt signaling controls regeneration polarity, with pathway components β-catenin-1 and wnt1 required to prevent head regeneration and promote tail regeneration at posterior-facing wounds. Wnt1 expression is upregulated near both anterior- and posterior-facing wounds. Notum (RNAi) animals regenerate an anterior-facing tail instead of a head, and double-RNAi experiments indicate notum inhibits Wnt signaling to promote head regeneration. notum expression is itself controlled by Wnt signaling, suggesting regulation of feedback inhibition controls the binary head-tail regeneration outcome.

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Ch. 22 - Prob. 1DQ Ch. 22 - Prob. 2DQ Ch. 22 - Prob. 3DQ

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