A poliomyelitis is a very infectious viral disease caused by polio virus and transmitted through feco-oral route from one person to another person. There is no cure for polio but can be prevented by immunization against polio virus. There are two types of Polio vaccines. 1. Oral polio vaccine (OPV) 2. Injectable polio vaccine (IPV) Oral polio vaccine is a live attenuated vaccine produced by passing poliovirus into nonhuman cells at sublevel temperature which causes mutations in viral genome spontaneously. It is otherwise called as sabin vaccine. Injectable polio vaccine is a inactivated poliovirus vaccine which provides immunoglobulin G mediated immunity in blood stream. It is 90% effective against all types of polio virus.

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Chapter 22, Problem 2A

Summary Introduction

Introduction:

A poliomyelitis is a very infectious viral disease caused by polio virus and transmitted through feco-oral route from one person to another person. There is no cure for polio but can be prevented by immunization against polio virus. There are two types of Polio vaccines.

1. Oral polio vaccine (OPV)

2. Injectable polio vaccine (IPV)

Oral polio vaccine is a live attenuated vaccine produced by passing poliovirus into nonhuman cells at sublevel temperature which causes mutations in viral genome spontaneously. It is otherwise called as sabin vaccine.

Injectable polio vaccine is a inactivated poliovirus vaccine which provides immunoglobulin G mediated immunity in blood stream. It is 90% effective against all types of polio virus.

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