Biochemistry 410/411 Textbook - 5th Edition - Custom Texas A&M University
Biochemistry 410/411 Textbook - 5th Edition - Custom Texas A&M University
5th Edition
ISBN: 9781119302940
Author: Voet
Publisher: WILEY C
bartleby

Concept explainers

bartleby

Videos

Question
Book Icon
Chapter 22, Problem 20E
Summary Introduction

To explain: The reason why the mice that are deficient in UCP1 become obese when raised at 28ºC but not at 20ºC.

Concept introduction: UCP1 or uncoupling protein, earlier named as thermogenin, is an uncoupling protein that is found in the mitochondria of brown adipose tissue. This uncoupling protein is used to generate heat by non-shivering thermogenesis. The methods to deliver UCP1 to cells by gene transfer therapy or the methods of its upregulation play an important role in the research for the treatment of obesity.

Blurred answer
Students have asked these similar questions
How does a voltage-gated sodium channel work? Specifically, how and why does a change in voltage trigger their opening? Please be detailed
When sodium ions enter a neuron during depolarization, they trigger the opening of additional voltage-gated sodium channels nearby, creating a positive feedback loop where the influx of sodium ions further depolarizes the membrane, causing even more sodium channels to open and allowing more sodium ions to enter the cell, thus sustaining the depolarization process until the action potential peaks. But how and why exactly does the influx of sodium ions trigger more sodium channels to let in more sodium? Please explain
Draw the chemical structure of the tripeptide, HEL (L - amino acids), at pH = 7.0. Calculate isoelectric point
Knowledge Booster
Background pattern image
Biochemistry
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Biochemistry
Biochemistry
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:W. H. Freeman
Text book image
Lehninger Principles of Biochemistry
Biochemistry
ISBN:9781464126116
Author:David L. Nelson, Michael M. Cox
Publisher:W. H. Freeman
Text book image
Fundamentals of Biochemistry: Life at the Molecul...
Biochemistry
ISBN:9781118918401
Author:Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:WILEY
Text book image
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Text book image
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Text book image
Fundamentals of General, Organic, and Biological ...
Biochemistry
ISBN:9780134015187
Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:PEARSON
Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY