Microbiology: An Introduction
12th Edition
ISBN: 9780321929150
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: PEARSON
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Textbook Question
Chapter 22, Problem 1R
If Clostridium tetani is relatively sensitive to penicillin, why doesn’t penicillin cure tetanus?
Expert Solution & Answer
Summary Introduction
To review:
Why penicillin does not cure tetanus.
Introduction:
Tetanus is an infectious disease caused by the bacteria named Clostridium tetani. It is a rod-shaped (bacillus), gram-positive, anaerobic, spore-forming bacteria.
Explanation of Solution
The anaerobic bacteria Clostridium tetani is sensitive to penicillin. However, adequate blood flow to the site of infection is necessary for penicillin to attain an optimum concentration at the site and to show maximum effectiveness. The causative pathogen is an obligate anaerobe and the wound by which it enters the body provide them an optimum anaerobic growth condition. Thus, due to the absence of enough blood flow, penicillin does not cure tetanus.
Conclusion
Tetanus infections commonly occur following a puncture wound exposed to the C. tetani bacteria. Contamination of the wound often involves contact with soil, fecal matter, or rusty metal containing the causative pathogen.
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Fig. 5-3: The Eco restriction site (left) would be cleaved at the locations indicated by the arrows.
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One of the SNPs in B. rapa is found within the Park14 locus and can be detected
by RFLP analysis. The CT polymorphism is found in the intron of the Bra013780
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EcoRI sites and thus is cleaved twice by EcoRI If there is a "T" in that SNP, one
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one EcoRI site (Fig. 5-3).
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with SNP(C)
Park14 allele
with SNPT)
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1101 EcoRI
839 EcoRI
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From your previous experiment, you found that this enhancer activates stripe 2 of eve expression. When you sequence this enhancer you find several binding sites for the gap gene, Giant. To test how Giant interacts with eve, you decide to remove all of the Giant binding sites from the eve enhancer. What results do you expect to see with respect to eve expression?
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Chapter 22 Solutions
Microbiology: An Introduction
Ch. 22 - If Clostridium tetani is relatively sensitive to...Ch. 22 - Prob. 2RCh. 22 - Prob. 3RCh. 22 - Prob. 4RCh. 22 - Prob. 5RCh. 22 - Prob. 6RCh. 22 - Prob. 7RCh. 22 - Prob. 8RCh. 22 - Provide evidence that Creutzfeldt-Jakob disease is...Ch. 22 - NAME IT This organism causes meningitis and is...
Ch. 22 - Prob. 1MCQCh. 22 - Prob. 2MCQCh. 22 - Prob. 3MCQCh. 22 - Prob. 4MCQCh. 22 - Prob. 5MCQCh. 22 - Prob. 6MCQCh. 22 - Prob. 7MCQCh. 22 - Prob. 8MCQCh. 22 - Microscopic examination of cerebrospinal fluid...Ch. 22 - Prob. 10MCQCh. 22 - Prob. 1ACh. 22 - Prob. 2ACh. 22 - Prob. 1CAECh. 22 - Prob. 2CAECh. 22 - Prob. 3CAE
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