The advantages of having increased levels of GLUT1 and phosphofructokinase in muscles for the adaptation in high altitudes. Concept introduction: GLUT 1 stands for glucose transporter 1, also called as solute carrier family 2. It was the first glucose transporter to be characterized. It helps in the transport of glucose across the plasma membrane of the mammalian cells. Phosphofructokinase is an enzyme that phosphorylates fructose 6-phosphate in the glycolysis.

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Answer 1

Question

Chapter 22, Problem 1E

Summary Introduction

To explain: The advantages of having increased levels of GLUT1 and phosphofructokinase in muscles for the adaptation in high altitudes.

Concept introduction: GLUT 1 stands for glucose transporter 1, also called as solute carrier family 2. It was the first glucose transporter to be characterized. It helps in the transport of glucose across the plasma membrane of the mammalian cells. Phosphofructokinase is an enzyme that phosphorylates fructose 6-phosphate in the glycolysis.

Expert Solution & Answer

Explanation of Solution

The lower air pressure in the high altitudes makes it more difficult for oxygen to enter the vascular systems. Therefore, oxygen availability for the aerobic metabolism is low. In these conditions, the anaerobic pathway glycolysis will become more important in the active muscles. Glucose transporter 1 transports the glucose across the plasma membrane. The increase in GLUT 1 increases the intracellular glucose concentration. An increase in level of the enzyme phosphofructokinase increases the flux of glucose through the pathway.

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Answer 2

Question

Chapter 22, Problem 1E

Summary Introduction

To explain: The advantages of having increased levels of GLUT1 and phosphofructokinase in muscles for the adaptation in high altitudes.

Concept introduction: GLUT 1 stands for glucose transporter 1, also called as solute carrier family 2. It was the first glucose transporter to be characterized. It helps in the transport of glucose across the plasma membrane of the mammalian cells. Phosphofructokinase is an enzyme that phosphorylates fructose 6-phosphate in the glycolysis.

Expert Solution & Answer

Explanation of Solution

The lower air pressure in the high altitudes makes it more difficult for oxygen to enter the vascular systems. Therefore, oxygen availability for the aerobic metabolism is low. In these conditions, the anaerobic pathway glycolysis will become more important in the active muscles. Glucose transporter 1 transports the glucose across the plasma membrane. The increase in GLUT 1 increases the intracellular glucose concentration. An increase in level of the enzyme phosphofructokinase increases the flux of glucose through the pathway.

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Answer 3

Question

Chapter 22, Problem 1E

Summary Introduction

To explain: The advantages of having increased levels of GLUT1 and phosphofructokinase in muscles for the adaptation in high altitudes.

Concept introduction: GLUT 1 stands for glucose transporter 1, also called as solute carrier family 2. It was the first glucose transporter to be characterized. It helps in the transport of glucose across the plasma membrane of the mammalian cells. Phosphofructokinase is an enzyme that phosphorylates fructose 6-phosphate in the glycolysis.

Expert Solution & Answer

Explanation of Solution

The lower air pressure in the high altitudes makes it more difficult for oxygen to enter the vascular systems. Therefore, oxygen availability for the aerobic metabolism is low. In these conditions, the anaerobic pathway glycolysis will become more important in the active muscles. Glucose transporter 1 transports the glucose across the plasma membrane. The increase in GLUT 1 increases the intracellular glucose concentration. An increase in level of the enzyme phosphofructokinase increases the flux of glucose through the pathway.

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Answer 4

Question

Chapter 22, Problem 1E

Summary Introduction

To explain: The advantages of having increased levels of GLUT1 and phosphofructokinase in muscles for the adaptation in high altitudes.

Concept introduction: GLUT 1 stands for glucose transporter 1, also called as solute carrier family 2. It was the first glucose transporter to be characterized. It helps in the transport of glucose across the plasma membrane of the mammalian cells. Phosphofructokinase is an enzyme that phosphorylates fructose 6-phosphate in the glycolysis.

Expert Solution & Answer

Explanation of Solution

The lower air pressure in the high altitudes makes it more difficult for oxygen to enter the vascular systems. Therefore, oxygen availability for the aerobic metabolism is low. In these conditions, the anaerobic pathway glycolysis will become more important in the active muscles. Glucose transporter 1 transports the glucose across the plasma membrane. The increase in GLUT 1 increases the intracellular glucose concentration. An increase in level of the enzyme phosphofructokinase increases the flux of glucose through the pathway.

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Answer 5

Chapter 22, Problem 1E

Summary Introduction

To explain: The advantages of having increased levels of GLUT1 and phosphofructokinase in muscles for the adaptation in high altitudes.

Concept introduction: GLUT 1 stands for glucose transporter 1, also called as solute carrier family 2. It was the first glucose transporter to be characterized. It helps in the transport of glucose across the plasma membrane of the mammalian cells. Phosphofructokinase is an enzyme that phosphorylates fructose 6-phosphate in the glycolysis.

Expert Solution & Answer

Explanation of Solution

The lower air pressure in the high altitudes makes it more difficult for oxygen to enter the vascular systems. Therefore, oxygen availability for the aerobic metabolism is low. In these conditions, the anaerobic pathway glycolysis will become more important in the active muscles. Glucose transporter 1 transports the glucose across the plasma membrane. The increase in GLUT 1 increases the intracellular glucose concentration. An increase in level of the enzyme phosphofructokinase increases the flux of glucose through the pathway.

Answer 6

Chapter 22, Problem 1E

Summary Introduction

To explain: The advantages of having increased levels of GLUT1 and phosphofructokinase in muscles for the adaptation in high altitudes.

Concept introduction: GLUT 1 stands for glucose transporter 1, also called as solute carrier family 2. It was the first glucose transporter to be characterized. It helps in the transport of glucose across the plasma membrane of the mammalian cells. Phosphofructokinase is an enzyme that phosphorylates fructose 6-phosphate in the glycolysis.

Expert Solution & Answer

Explanation of Solution

The lower air pressure in the high altitudes makes it more difficult for oxygen to enter the vascular systems. Therefore, oxygen availability for the aerobic metabolism is low. In these conditions, the anaerobic pathway glycolysis will become more important in the active muscles. Glucose transporter 1 transports the glucose across the plasma membrane. The increase in GLUT 1 increases the intracellular glucose concentration. An increase in level of the enzyme phosphofructokinase increases the flux of glucose through the pathway.

Answer 7

Chapter 22, Problem 1E

Summary Introduction

To explain: The advantages of having increased levels of GLUT1 and phosphofructokinase in muscles for the adaptation in high altitudes.

Concept introduction: GLUT 1 stands for glucose transporter 1, also called as solute carrier family 2. It was the first glucose transporter to be characterized. It helps in the transport of glucose across the plasma membrane of the mammalian cells. Phosphofructokinase is an enzyme that phosphorylates fructose 6-phosphate in the glycolysis.

Answer 8

Expert Solution & Answer

Explanation of Solution

The lower air pressure in the high altitudes makes it more difficult for oxygen to enter the vascular systems. Therefore, oxygen availability for the aerobic metabolism is low. In these conditions, the anaerobic pathway glycolysis will become more important in the active muscles. Glucose transporter 1 transports the glucose across the plasma membrane. The increase in GLUT 1 increases the intracellular glucose concentration. An increase in level of the enzyme phosphofructokinase increases the flux of glucose through the pathway.

Answer 9

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Answer 10

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Answer 11

Ch. 22 - Prob. 1E Ch. 22 - Prob. 2E Ch. 22 - 3. Toxins that occur in certain mushrooms block ?...Ch. 22 - Prob. 4E Ch. 22 - 5. The passive glucose transporter named GLUT1...Ch. 22 - Prob. 6E Ch. 22 - Prob. 7E Ch. 22 - 8. (a) Identify the two reactions that allow the...Ch. 22 - Prob. 9E Ch. 22 - Prob. 10E

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