The reagents that are used to convert from compounds 1 to 5 have to be determined. Concept Introduction: Stork enamine reaction: It is the reaction in which a ketone or cyclic ketone will get installed with a side chain group via enamine formation and Michael addition. General scheme: Michael addition: It is the 1,4 addition of an enolate to an alpha beta unsaturated compounds to form a difunctionalized compound. In this the enolate with the negative charge acts as a nucleophile while the alpha beta unsaturated compound with a double bond acts as an electrophile. In Michael addition, the nucleophilic species is called the Michael donor whereas the electrophilic species is called the Michael acceptor . Example: Wittig reaction: It is the conversion of ketone into alkene using phosphonium ylide. Example: Hydrolysis of nitriles: Nitriles on hydrolysis get converted into carboxylic acids. General scheme:

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Answer 1

Question

Chapter 21.6, Problem 39ATS

Interpretation Introduction

Interpretation:

The reagents that are used to convert from compounds 1 to 5 have to be determined.

Concept Introduction:

Stork enamine reaction:

It is the reaction in which a ketone or cyclic ketone will get installed with a side chain group via enamine formation and Michael addition.

General scheme:

Michael addition:

It is the 1,4 addition of an enolate to an alpha beta unsaturated compounds to form a difunctionalized compound. In this the enolate with the negative charge acts as a nucleophile while the alpha beta unsaturated compound with a double bond acts as an electrophile. In Michael addition, the nucleophilic species is called the Michael donor whereas the electrophilic species is called the Michael acceptor.

Example:

Wittig reaction:

It is the conversion of ketone into alkene using phosphonium ylide.

Example:

Hydrolysis of nitriles:

Nitriles on hydrolysis get converted into carboxylic acids.

General scheme:

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Answer 2

Question

Chapter 21.6, Problem 39ATS

Interpretation Introduction

Interpretation:

The reagents that are used to convert from compounds 1 to 5 have to be determined.

Concept Introduction:

Stork enamine reaction:

It is the reaction in which a ketone or cyclic ketone will get installed with a side chain group via enamine formation and Michael addition.

General scheme:

Michael addition:

It is the 1,4 addition of an enolate to an alpha beta unsaturated compounds to form a difunctionalized compound. In this the enolate with the negative charge acts as a nucleophile while the alpha beta unsaturated compound with a double bond acts as an electrophile. In Michael addition, the nucleophilic species is called the Michael donor whereas the electrophilic species is called the Michael acceptor.

Example:

Wittig reaction:

It is the conversion of ketone into alkene using phosphonium ylide.

Example:

Hydrolysis of nitriles:

Nitriles on hydrolysis get converted into carboxylic acids.

General scheme:

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 3

Question

Chapter 21.6, Problem 39ATS

Interpretation Introduction

Interpretation:

The reagents that are used to convert from compounds 1 to 5 have to be determined.

Concept Introduction:

Stork enamine reaction:

It is the reaction in which a ketone or cyclic ketone will get installed with a side chain group via enamine formation and Michael addition.

General scheme:

Michael addition:

It is the 1,4 addition of an enolate to an alpha beta unsaturated compounds to form a difunctionalized compound. In this the enolate with the negative charge acts as a nucleophile while the alpha beta unsaturated compound with a double bond acts as an electrophile. In Michael addition, the nucleophilic species is called the Michael donor whereas the electrophilic species is called the Michael acceptor.

Example:

Wittig reaction:

It is the conversion of ketone into alkene using phosphonium ylide.

Example:

Hydrolysis of nitriles:

Nitriles on hydrolysis get converted into carboxylic acids.

General scheme:

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 21.6, Problem 39ATS

Interpretation Introduction

Interpretation:

The reagents that are used to convert from compounds 1 to 5 have to be determined.

Concept Introduction:

Stork enamine reaction:

It is the reaction in which a ketone or cyclic ketone will get installed with a side chain group via enamine formation and Michael addition.

General scheme:

Michael addition:

It is the 1,4 addition of an enolate to an alpha beta unsaturated compounds to form a difunctionalized compound. In this the enolate with the negative charge acts as a nucleophile while the alpha beta unsaturated compound with a double bond acts as an electrophile. In Michael addition, the nucleophilic species is called the Michael donor whereas the electrophilic species is called the Michael acceptor.

Example:

Wittig reaction:

It is the conversion of ketone into alkene using phosphonium ylide.

Example:

Hydrolysis of nitriles:

Nitriles on hydrolysis get converted into carboxylic acids.

General scheme:

Expert Solution & Answer

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Check out a sample textbook solution

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Answer 5

Chapter 21.6, Problem 39ATS

Interpretation Introduction

Interpretation:

The reagents that are used to convert from compounds 1 to 5 have to be determined.

Concept Introduction:

Stork enamine reaction:

It is the reaction in which a ketone or cyclic ketone will get installed with a side chain group via enamine formation and Michael addition.

General scheme:

Michael addition:

It is the 1,4 addition of an enolate to an alpha beta unsaturated compounds to form a difunctionalized compound. In this the enolate with the negative charge acts as a nucleophile while the alpha beta unsaturated compound with a double bond acts as an electrophile. In Michael addition, the nucleophilic species is called the Michael donor whereas the electrophilic species is called the Michael acceptor.

Example:

Wittig reaction:

It is the conversion of ketone into alkene using phosphonium ylide.

Example:

Hydrolysis of nitriles:

Nitriles on hydrolysis get converted into carboxylic acids.

General scheme:

Answer 6

Chapter 21.6, Problem 39ATS

Interpretation Introduction

Interpretation:

The reagents that are used to convert from compounds 1 to 5 have to be determined.

Concept Introduction:

Stork enamine reaction:

It is the reaction in which a ketone or cyclic ketone will get installed with a side chain group via enamine formation and Michael addition.

General scheme:

Michael addition:

It is the 1,4 addition of an enolate to an alpha beta unsaturated compounds to form a difunctionalized compound. In this the enolate with the negative charge acts as a nucleophile while the alpha beta unsaturated compound with a double bond acts as an electrophile. In Michael addition, the nucleophilic species is called the Michael donor whereas the electrophilic species is called the Michael acceptor.

Example:

Wittig reaction:

It is the conversion of ketone into alkene using phosphonium ylide.

Example:

Hydrolysis of nitriles:

Nitriles on hydrolysis get converted into carboxylic acids.

General scheme:

Answer 7

Chapter 21.6, Problem 39ATS

Interpretation Introduction

Interpretation:

The reagents that are used to convert from compounds 1 to 5 have to be determined.

Concept Introduction:

Stork enamine reaction:

It is the reaction in which a ketone or cyclic ketone will get installed with a side chain group via enamine formation and Michael addition.

General scheme:

Michael addition:

It is the 1,4 addition of an enolate to an alpha beta unsaturated compounds to form a difunctionalized compound. In this the enolate with the negative charge acts as a nucleophile while the alpha beta unsaturated compound with a double bond acts as an electrophile. In Michael addition, the nucleophilic species is called the Michael donor whereas the electrophilic species is called the Michael acceptor.

Example:

Wittig reaction:

It is the conversion of ketone into alkene using phosphonium ylide.

Example:

Hydrolysis of nitriles:

Nitriles on hydrolysis get converted into carboxylic acids.

General scheme:

Answer 8

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Answer 11

Ch. 21.1 - Prob. 1CC Ch. 21.1 - Prob. 2CC Ch. 21.1 - Prob. 3CC Ch. 21.1 - Prob. 1LTS Ch. 21.1 - Prob. 4PTS Ch. 21.1 - APPLY the skill As with aldehydes and ketones, the...Ch. 21.1 - Draw the enolate ion that is formed when each of...Ch. 21.1 - Prob. 7CC Ch. 21.2 - Prob. 8CC Ch. 21.2 - Prob. 9CC

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