EP BIOLOGY:SCIENCE F/LIFE...-MOD.ACCESS
6th Edition
ISBN: 9780134839530
Author: BELK
Publisher: PEARSON CO
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Chapter 21, Problem 3AAATB
Summary Introduction
To determine:
The reason for the requirement of flu shot every year but there is a requirement of only a single inoculation against some other diseases.
Introduction:
The immune system can be defined as the organs and body processes that resist the infection and toxins. Flu or influenza is a respiratory disease that is caused by a virus. It is extremely contagious and is usually spread by the sneezes and coughs of an infected person.
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Kinetics: One-Compartment First-Order Absorption
1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration.
Using this data and set of graphs, determine:(calculate for each variable)
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c) k, ka, B1, and AUC* for the ip data
(d) relative bioavailability for po vs ip, Fpo/Fip
(e)absolute ip bioavailability, Fip
(f) absolute po bioavailability, Fpo
Chapter 21 Solutions
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