Human Anatomy & Physiology, Books a la Carte Edition (11th Edition)
11th Edition
ISBN: 9780134807423
Author: Elaine N. Marieb, Katja Hoehn
Publisher: PEARSON
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Chapter 21, Problem 2CCS
52-Year-Old Male with Multiple Sclerosis
Mr. Ayers was diagnosed with an aggressive form of multiple sclerosis 18 years ago. His illness has not responded to conventional treatments so he's been referred to your clinic for a clinical trial.
The doctor explains that his treatment will involve giving Mr. Ayers a drug that will release stem cells from his bone marrow so they can be collected from his blood. Then Mr. Ayers will be given (1) drugs that will destroy the blood-forming cells in his bone marrow, and (2), antibodies against his T lymphocytes. Finally, the stem cells that were collected from him will be used to repopulate his bone marrow.
The doctor says, “This treatment avoids problems, such as transplant rejection, that are associated with other kinds of transplants.”
2. One reason for using Mr. Ayers's own tissue is that it can be very difficult to find a donor whose bone marrow cells match the patient's class I and II MHC proteins. What is an MHC protein? What is the difference between class I and class II MHC proteins?
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Chapter 21 Solutions
Human Anatomy & Physiology, Books a la Carte Edition (11th Edition)
Ch. 21 - Prob. 1RQCh. 21 - 2. The process by which neutrophils squeeze...Ch. 21 - 3. Antibodies released by plasma cells are...Ch. 21 - 5. Which antibody class is abundant in body...Ch. 21 - Prob. 5RQCh. 21 - Prob. 6RQCh. 21 - Prob. 7RQCh. 21 - Prob. 8RQCh. 21 - 9. Complement activation promotes all of the...Ch. 21 - 10. The cell type most often invaded by HIV is...
Ch. 21 - Prob. 10RQCh. 21 - 13. Besides acting as mechanical barriers, the...Ch. 21 - 15. What is complement? How does it cause...Ch. 21 - Prob. 15RQCh. 21 - Prob. 24RQCh. 21 - Prob. 25RQCh. 21 - Prob. 16RQCh. 21 - Prob. 17RQCh. 21 - Prob. 18RQCh. 21 - Prob. 12RQCh. 21 - 24. How do antibodies help defend the body?
Ch. 21 - Prob. 20RQCh. 21 - Prob. 21RQCh. 21 - Prob. 22RQCh. 21 - Prob. 23RQCh. 21 - 1. Isabella, a 6-year-old child who has been...Ch. 21 - Prob. 27RQCh. 21 - Prob. 28RQCh. 21 - 52-Year-Old Male with Multiple Sclerosis Mr. Ayers...Ch. 21 - 52-Year-Old Male with Multiple Sclerosis Mr. Ayers...Ch. 21 - 52-Year-Old Male with Multiple Sclerosis Mr. Ayers...Ch. 21 - 52-Year-Old Male with Multiple Sclerosis
Mr....
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