HOLE'S HUMAN ANATOMY >PRINT UPGRADE<
15th Edition
ISBN: 9781266019142
Author: SHIER
Publisher: MCG
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Chapter 21, Problem 2CA
Summary Introduction
Introduction:
The fluid present in the body is classified into two forms, which are:intracellular and extracellular fluid. The intracellular fluid is the fluid that is enclosed within the cell membrane of all the body cells. The extracellular fluid is the fluid that is present outside the cell membrane of all the body cells.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 21 Solutions
HOLE'S HUMAN ANATOMY >PRINT UPGRADE<
Ch. 21 - Prob. 1PCh. 21 - Prob. 2PCh. 21 - Prob. 3PCh. 21 - Prob. 4PCh. 21 - Prob. 5PCh. 21 - Prob. 6PCh. 21 - Prob. 7PCh. 21 - Prob. 8PCh. 21 - Prob. 9PCh. 21 - Prob. 10P
Ch. 21 - What is the primary regulator of water loss?Ch. 21 - Prob. 12PCh. 21 - Prob. 13PCh. 21 - Prob. 14PCh. 21 - Which mechanism ordinarily regulate electrolyte...Ch. 21 - Prob. 16PCh. 21 - Prob. 17PCh. 21 - Prob. 18PCh. 21 - Prob. 19PCh. 21 - Prob. 20PCh. 21 - Prob. 21PCh. 21 - Prob. 22PCh. 21 - Prob. 23PCh. 21 - Prob. 24PCh. 21 - Prob. 25PCh. 21 - Prob. 26PCh. 21 - Prob. 27PCh. 21 - Prob. 28PCh. 21 - Prob. 29PCh. 21 - Prob. 30PCh. 21 - Prob. 1CACh. 21 - Prob. 2CACh. 21 - Prob. 3CACh. 21 - Prob. 4CACh. 21 - Prob. 5CACh. 21 - Prob. 6CACh. 21 - Prob. 7CACh. 21 - Prob. 8CACh. 21 - Prob. 9CACh. 21 - Prob. 10CACh. 21 - Prob. 11CACh. 21 - Prob. 12CACh. 21 - Prob. 13CACh. 21 - Prob. 14CACh. 21 - Prob. 15CACh. 21 - Prob. 16CACh. 21 - Prob. 17CACh. 21 -
18 _________ dissociate to release fewer...Ch. 21 -
19 Explain how an acid-base buffer system...Ch. 21 - Explain how the bicarbonate buffer system resists...Ch. 21 -
21 Explain why a protein has both acidic and...Ch. 21 - Prob. 22CACh. 21 - Describe the role of hemoglobin as buffer . (p....Ch. 21 - Prob. 24CACh. 21 - Prob. 25CACh. 21 - Prob. 26CACh. 21 - Distinguish between a chemical buffer system and a...Ch. 21 - Distinguish between respiratory and metabolic...Ch. 21 - Prob. 29CACh. 21 - Prob. 1IACh. 21 - Prob. 2IACh. 21 - Prob. 3IACh. 21 - Prob. 4IACh. 21 - Prob. 5IA
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