Study Guide with Student Solutions Manual for Seager/Slabaugh/Hansen's Chemistry for Today: General, Organic, and Biochemistry, 9th Edition
9th Edition
ISBN: 9781305968608
Author: Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Publisher: Cengage Learning
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Chapter 21, Problem 21.70E
Interpretation Introduction
Interpretation:
The components of the
Concept introduction:
The term DNA stands for deoxyribonucleic acid. This is the most important
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Learning Goal:
As discussed during the lecture, the enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT.
The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7).
Part A - Difference in binding free eenergies
Compute the difference in binding free energy (at a physiological temperature T=310 K) for the complexes. Provide the difference as a positive numerical expression with three significant figures in kJ/mol.
The margin of error is 2%.
Part B - Compare difference in free energy to the thermal energy
Divide the…
Please correct answer and don't used hand raiting
Please correct answer and don't used hand raiting
Chapter 21 Solutions
Study Guide with Student Solutions Manual for Seager/Slabaugh/Hansen's Chemistry for Today: General, Organic, and Biochemistry, 9th Edition
Ch. 21 - What is the principal location of DNA within the...Ch. 21 - Which pentose sugar is present in DNA? In RNA?Ch. 21 - Prob. 21.3ECh. 21 - Prob. 21.4ECh. 21 - Prob. 21.5ECh. 21 - Prob. 21.6ECh. 21 - Prob. 21.7ECh. 21 - Identify the 3 and 5 ends of the DNA segment...Ch. 21 - Prob. 21.9ECh. 21 - Prob. 21.10E
Ch. 21 - Describe the role of hydrogen bonding in the...Ch. 21 - How many total hydrogen bonds would exist between...Ch. 21 - How many total hydrogen bonds would exist between...Ch. 21 - Prob. 21.14ECh. 21 - A strand of DNA has the base sequence GATTCA....Ch. 21 - What is a chromosome? How many chromosomes are in...Ch. 21 - Prob. 21.17ECh. 21 - What is a replication fork?Ch. 21 - Prob. 21.19ECh. 21 - List the steps involved in DNA replication.Ch. 21 - What enzymes are involved in DNA replication?Ch. 21 - In what direction is a new DNA strand formed?Ch. 21 - Prob. 21.23ECh. 21 - Prob. 21.24ECh. 21 - Prob. 21.25ECh. 21 - How does the sugar-phosphate backbone of RNA...Ch. 21 - Compare the secondary structures of RNA and DNA.Ch. 21 - Briefly describe the characteristics and functions...Ch. 21 - Must the ratio of guanine to cytosine be 1:1 in...Ch. 21 - What are the two important regions of a tRNA...Ch. 21 - Prob. 21.31ECh. 21 - In the flow of genetic information, what is meant...Ch. 21 - Prob. 21.33ECh. 21 - Write the base sequence for the mRNA that would be...Ch. 21 - Prob. 21.35ECh. 21 - What is the relationship among exons, introns, and...Ch. 21 - What is a codon?Ch. 21 - For each of the following mRNA codons, give the...Ch. 21 - Describe the experiment that allowed researchers...Ch. 21 - Which of the following statements about the...Ch. 21 - The -chain of hemoglobin is a protein that...Ch. 21 - Prob. 21.42ECh. 21 - Prob. 21.43ECh. 21 - Prob. 21.44ECh. 21 - Prob. 21.45ECh. 21 - Prob. 21.46ECh. 21 - Prob. 21.47ECh. 21 - Prob. 21.48ECh. 21 - Prob. 21.49ECh. 21 - Prob. 21.50ECh. 21 - Prob. 21.51ECh. 21 - Prob. 21.52ECh. 21 - Prob. 21.53ECh. 21 - Prob. 21.54ECh. 21 - Prob. 21.55ECh. 21 - Prob. 21.56ECh. 21 - Prob. 21.57ECh. 21 - Prob. 21.58ECh. 21 - Prob. 21.59ECh. 21 - Genetic engineering shows great promise for the...Ch. 21 - Prob. 21.61ECh. 21 - Prob. 21.62ECh. 21 - Prob. 21.63ECh. 21 - Prob. 21.64ECh. 21 - Prob. 21.65ECh. 21 - Prob. 21.66ECh. 21 - How does the DNA content determine what reactions...Ch. 21 - What would be the ramifications if DNA were single...Ch. 21 - Prob. 21.69ECh. 21 - Prob. 21.70ECh. 21 - Explain the function and importance of each of the...Ch. 21 - Prob. 21.72ECh. 21 - Which base is found in DNA but not in RNA? a....Ch. 21 - Which of the following best describes tRNA? a. It...Ch. 21 - Which of the following is the site of protein...Ch. 21 - In messenger RNA, a codon contains how many...
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Nucleic acids - DNA and RNA structure; Author: MEDSimplified;https://www.youtube.com/watch?v=0lZRAShqft0;License: Standard YouTube License, CC-BY