Chapter 21, Problem 21.26P

Interpretation Introduction

Interpretation:

Synthetic approach to synthesize the given compound without using ester of the form given below via Claisen-Condensation is to proposed

Concept introduction:

Caisen condensation can be self Claisen condensation or cross Claisen condensation. In self condensation, two precursors are identical while in cross, they are different.

Here, retrosynthesis of the product suggests that it is a product of cross Claisen condensation. In cross condensation, one precursor should be an ester or ketone that cannot form enolate, and another which can form enolate.