EBK HUMAN BIOLOGY
11th Edition
ISBN: 8220100545931
Author: MCMILLAN
Publisher: Cengage Learning US
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Chapter 21, Problem 1RQ
Why is
Expert Solution & Answer
Summary Introduction
To explain: The reason why DNA replication is called “semiconservative”.
Introduction: Deoxyribonucleic acid (DNA) is the genetic material of prokaryotes, archaea, eukaryotes, and some viruses. Replication of DNA results in two copies of DNA that are split into two cells at the end of cell division. Replication is the starting mechanism in the central dogma.
Explanation of Solution
There are three proposed models of DNA replication:
- • Conservative model
- • Semiconservative model
- • Dispersive model.
Semiconservative model is the widely accepted and experimentally proved model. According to this model, each copy of the DNA replicated contains a parent strand.
Meselson–Stahl experiment supported the Watson and Crick model of DNA and provided evidences for semiconservative model of DNA replication.
In semiconservative replication, the two strands of parental DNA are used as a template each and a new strand is synthesized with enzymes and nucleotides. Thus, each daughter strand has a parental strand and a newly synthesized strand. Since a parental strand is conserved in daughter DNA, it is called semiconservative DNA replication.
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The metabolic pathway below is used for the production of the purine nucleotides adenosine monophosphate (AMP) and guanosine monophosphate (GMP) in eukaryotic cells. Assume each arrow represents a reaction catalyzed by a different enzyme. Using the principles of feedback inhibition, propose a regulatory scheme for this pathway that ensures an adequate supply of both AMP and GMP, and prevents the buildup of Intermediates A through G when supplies of both AMP and GMP are adequate.
QUESTION 27
Label the structures marked A, B, C and explain the role of structure A.
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plasma membrane
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