
Concept explainers
To explain: The reason why in the absence of Delta, cells become unsynchronized and somites are not formed completely.
Concept introduction: In Delta–Notch signaling, Delta from the adjacent cell binds to notch receptor. Intracellular notch tail cleaves and enters the nucleus for transcription. Her7 is an important transcription factor required for somite development in zebra fishes. Delta–Notch signaling activates the Her7 transcription.
To explain: The presence of Delta keeps adjacent cells oscillating in synchrony.
Concept introduction: In Delta–Notch signaling, Delta from the adjacent cell binds to notch receptor. Intracellular notch tail cleaves and enters the nucleus for transcription. Her7 is an important transcription factor required for somite development in zebra fishes. Delta–Notch signaling activates the Her7 transcription.

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Chapter 21 Solutions
Molecular Biology of the Cell (Sixth Edition)
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