Molecular Biology of the Cell (Sixth Edition)
6th Edition
ISBN: 9780815344322
Author: Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher: W. W. Norton & Company
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Chapter 21, Problem 13P
Summary Introduction
To explain: HoxA3 and HoxD3 genes are nearly equivalent yet they play distinct roles in the development of mouse.
Concept introduction: Hox genes belong to the Homeobox family of genes which play a crucial role in the development of organisms and several genes of the homeobox genes are conserved through evolution. HoxA3 is expressed in the pharynx, colon, ovary and many more. HoxD3 is expressed in the ovary, genital fat pad and many more. Cis- regulatory sequences or elements are non-coding regions present in the DNA and control the transcription of neighboring coding-regions present in DNA sequences.
Summary Introduction
To explain: The reason why the genes when transplaced could not perform their normal function in a new location.
Concept introduction: Hox genes belong to the Homeobox family of genes which play a crucial role in the development of organisms and several genes of the homeobox genes are conserved through evolution. HoxA3 is expressed in the pharynx, colon, ovary and many more. HoxD3 is expressed in the ovary, genital fat pad and many more. Cis- regulatory sequences or elements are non-coding regions present in the DNA and control the transcription of neighboring coding-regions present in DNA sequences.
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Molecular Biology of the Cell (Sixth Edition)
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