One reason for the irreversibility of the in vivo phosphorolysis should be stated. Concept introduction: The Le Chatelier’s principle is applied to the phosphorolysis reaction to identify the reason for the irreversibility of the in vivo phosphorolysis. Le Chatelier’s principle simply states that when a constraint such as a change in concentration is applied to an equilibrated system (e.g. a reversible reaction), the equilibrium shifts to minimize the applied constraint.

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Chapter 21, Problem 12P

Interpretation Introduction

Interpretation:

One reason for the irreversibility of the in vivo phosphorolysis should be stated.

Concept introduction:

The Le Chatelier’s principle is applied to the phosphorolysis reaction to identify the reason for the irreversibility of the in vivo phosphorolysis.

Le Chatelier’s principle simply states that when a constraint such as a change in concentration is applied to an equilibrated system (e.g. a reversible reaction), the equilibrium shifts to minimize the applied constraint.

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