One reason for the irreversibility of the in vivo phosphorolysis should be stated. Concept introduction: The Le Chatelier’s principle is applied to the phosphorolysis reaction to identify the reason for the irreversibility of the in vivo phosphorolysis. Le Chatelier’s principle simply states that when a constraint such as a change in concentration is applied to an equilibrated system (e.g. a reversible reaction), the equilibrium shifts to minimize the applied constraint.

Question

Want to see the full answer?

Answer 1

Question

Chapter 21, Problem 12P

Interpretation Introduction

Interpretation:

One reason for the irreversibility of the in vivo phosphorolysis should be stated.

Concept introduction:

The Le Chatelier’s principle is applied to the phosphorolysis reaction to identify the reason for the irreversibility of the in vivo phosphorolysis.

Le Chatelier’s principle simply states that when a constraint such as a change in concentration is applied to an equilibrated system (e.g. a reversible reaction), the equilibrium shifts to minimize the applied constraint.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Pyruvate is accepted into the TCA cycle by a “feeder” reaction using the pyruvatedehydrogenase complex, resulting in acetyl-CoA and CO2. Provide a full mechanismfor this reaction utilizing the TPP cofactor. Include the roles of all cofactors.

B- Vitamins are converted readily into important metabolic cofactors. Deficiency inany one of them has serious side effects. a. The disease beriberi results from a vitamin B 1 (Thiamine) deficiency and ischaracterized by cardiac and neurological symptoms. One key diagnostic forthis disease is an increased level of pyruvate and α-ketoglutarate in thebloodstream. How does this vitamin deficiency lead to increased serumlevels of these factors? b. What would you expect the effect on the TCA intermediates for a patientsuffering from vitamin B 5 deficiency? c. What would you expect the effect on the TCA intermediates for a patientsuffering from vitamin B 2 /B 3 deficiency?

Draw the Krebs Cycle and show the entry points for the amino acids Alanine,Glutamic Acid, Asparagine, and Valine into the Krebs Cycle - (Draw the Mechanism). How many rounds of Krebs will be required to waste all Carbons of Glutamic Acidas CO2?