The amino acid sequence of the normal and the mutant proteins when a gene that contains the sequences AUGCCCGACUUU undergoes point mutation to give the gene AUGC G _ CGACUUU has to be determined. Also, whether the mutation is a silent mutation or not has to be identified. Concept Introduction: The point mutation is defined as the mutation that results from the replacement of single nucleotide from the codon triplet. For instance, if the UUU codon that codes for phenylalanine.is replaced by the codon UUA it would code for leucine. Silent mutations are the point mutations that do not affect the amino acid being encoded. For example, a silent mutation that results in the replacement of leucine with isoleucine has no significant effect on the protein’s function as isoleucine uses the same functionality as that of leucine.

Question

Want to see the full answer?

Answer 1

Question

Chapter 20.7, Problem 20.11Q

Interpretation Introduction

Interpretation:

The amino acid sequence of the normal and the mutant proteins when a gene that contains the sequences AUGCCCGACUUU undergoes point mutation to give the gene AUGCG_CGACUUU has to be determined. Also, whether the mutation is a silent mutation or not has to be identified.

Concept Introduction:

The point mutation is defined as the mutation that results from the replacement of single nucleotide from the codon triplet. For instance, if the UUU codon that codes for phenylalanine.is replaced by the codon UUA it would code for leucine.

Silent mutations are the point mutations that do not affect the amino acid being encoded. For example, a silent mutation that results in the replacement of leucine with isoleucine has no significant effect on the protein’s function as isoleucine uses the same functionality as that of leucine.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

#1. Retro-Electrochemical Reaction: A ring has been made, but the light is causing the molecule to un- cyclize. Undo the ring into all possible molecules. (2pts, no partial credit) hv

Don't used Ai solution

I have a question about this problem involving mechanisms and drawing curved arrows for acids and bases. I know we need to identify the nucleophile and electrophile, but are there different types of reactions? For instance, what about Grignard reagents and other types that I might not be familiar with? Can you help me with this? I want to identify the names of the mechanisms for problems 1-14, such as Gilman reagents and others. Are they all the same? Also, could you rewrite it so I can better understand? The handwriting is pretty cluttered. Additionally, I need to label the nucleophile and electrophile, but my main concern is whether those reactions differ, like the "Brønsted-Lowry acid-base mechanism, Lewis acid-base mechanism, acid-catalyzed mechanisms, acid-catalyzed reactions, base-catalyzed reactions, nucleophilic substitution mechanisms (SN1 and SN2), elimination reactions (E1 and E2), organometallic mechanisms, and so forth."