HUMAN BIOLOGY (LOOSELEAF)-W/CONNECT
16th Edition
ISBN: 9781260692174
Author: Mader
Publisher: MCG
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Chapter 20.3, Problem 3CYP
Summary Introduction
To discuss:
How genetic tests and tumor marker tests may be used to prevent cancer.
Introduction:
Early diagnosis of cancer is crucial for its treatment. Cancer can be easily detected by performing some tests which are easy to do and are accurate. Some commonly done tests are routine screening tests, tumor marker tests, genetic tests, PAP tests, etc.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 20 Solutions
HUMAN BIOLOGY (LOOSELEAF)-W/CONNECT
Ch. 20.1 - Descrihe the characteristics of cancer cells that...Ch. 20.1 - Prob. 2LOCh. 20.1 - Prob. 3LOCh. 20.1 - Prob. 1BTSCh. 20.1 - Prob. 2BTSCh. 20.1 - List the characteristics of cancer cells that...Ch. 20.1 - Describe how mutations in tumor suppressor genes...Ch. 20.1 - Prob. 3CYPCh. 20.2 - Prob. 1LOCh. 20.2 - Prob. 2LO
Ch. 20.2 - Summarize how protective behaviors and diet can...Ch. 20.2 - Prob. 1BTHCh. 20.2 - Prob. 2BTHCh. 20.2 - Prob. 1CYPCh. 20.2 - List the environmental carcinogens that are known...Ch. 20.2 - Prob. 3CYPCh. 20.3 - Prob. 1LOCh. 20.3 - Prob. 2LOCh. 20.3 - Prob. 1CYPCh. 20.3 - Identify the routine screening tests that are...Ch. 20.3 - Prob. 3CYPCh. 20.4 - Prob. 1LOCh. 20.4 - Prob. 2LOCh. 20.4 - Describe the three types of therapy that are...Ch. 20.4 - Discuss why cancer treatment may involve a...Ch. 20.4 - Prob. 3CYPCh. 20 - Prob. 1ACh. 20 - Prob. 2ACh. 20 - Angiogenesis stimulates the development of new...Ch. 20 - Prob. 4ACh. 20 - 5. Concerning the causes of cancer, which one is...Ch. 20 - Prob. 6ACh. 20 - Prob. 7ACh. 20 - Prob. 8ACh. 20 - Prob. 9ACh. 20 - Prob. 10ACh. 20 - Prob. 1TCCh. 20 - Prob. 2TCCh. 20 - Prob. 3TCCh. 20 - Prob. 4TCCh. 20 - Prob. 5TC
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