Understanding Pathophysiology, 6e
Understanding Pathophysiology, 6e
6th Edition
ISBN: 9780323354097
Author: Sue E. Huether RN PhD, Kathryn L. McCance RN PhD
Publisher: Elsevier Science
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Chapter 20.1, Problem 1QC
Summary Introduction

To explain: The unique properties of erythrocyte’s shape.

Concept introduction: Erythrocytes (Red blood cells-RBC) are involved in the transport of oxygen to the cells. The cytoplasm of RBC is rich in the hemoglobin. The prefix heme- is the iron-containing pigment and globin is the protein part.

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Explanation of Solution

Erythrocytes are responsible for the oxygenation of tissues. Erythrocytes contain a distinctive protein called hemoglobin that carries gases and electrolytes through the plasma membrane of the cell. In the human, the mature erythrocytes lack a nucleus and cytoplasmic organelles like mitochondria. The size and shape of the erythrocyte are unique as it is well-suited to its function. Its main function is a gaseous exchange. Erythrocytes are small and disk-shaped. The unique properties of the erythrocyte’s shape are as follows:

  • A biconcave shape
  • Cell deformity
  • Stability

A biconcave shape provides an extra surface area or the volume ratio that allows the change of in the shape without increasing the surface area of the erythrocytes. It optimizes the gaseous diffusion and flow of blood in the large vessels. The deformability of erythrocytes is its ability to change the shape under the stress conditions. They change its shape under the influence of mechanical forces that can pass through a microcirculation. Thus, it promotes the mechanical stability of erythrocytes especially when they are passed through the capillary network.

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