EP BIOLOGY:SCIENCE F/LIFE...-MOD.ACCESS
6th Edition
ISBN: 9780134839530
Author: BELK
Publisher: PEARSON CO
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Chapter 20, Problem 4LTB
Summary Introduction
Introduction:
The heart is the muscular organ which is approximately the size of one’s fist. It is located behind and slightly left of the breastbone. The function of the heart is to pump the blood by arteries and veins. The whole network of arteries, veins, and heart is termed as cardiovascular system.
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Kinetics: One-Compartment First-Order Absorption
1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration.
Using this data and set of graphs, determine:(calculate for each variable)
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(b) k, ka, B1, and AUC* for the po data
c) k, ka, B1, and AUC* for the ip data
(d) relative bioavailability for po vs ip, Fpo/Fip
(e)absolute ip bioavailability, Fip
(f) absolute po bioavailability, Fpo
Chapter 20 Solutions
EP BIOLOGY:SCIENCE F/LIFE...-MOD.ACCESS
Ch. 20 - Describe how contraction of the diaphragm allows...Ch. 20 - Prob. 2LTBCh. 20 - Alveoli are ___________. small air sacs at the...Ch. 20 - Prob. 4LTBCh. 20 - Prob. 5LTBCh. 20 - Prob. 6LTBCh. 20 - Prob. 7LTBCh. 20 - Prob. 8LTBCh. 20 - Heart attacks ___________. are typically caused by...Ch. 20 - Prob. 10LTB
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