The ratio of NADPH to NADP+ required to sustain given conditions should be determined. Concept introduction: Reduced glutathione (GSH) is a tripeptide with a sulfhydryl group. GSH reduces reactive oxygen species to harmless forms, thereby reducing the oxidative stress in the cell. This prevents the cell from various damages and cell death. When ROS are reduced, GSH is oxidized GSSG. In order to continue this ROS removal process GSH should be regenerated. So, GSSG is again reduced into GSH by NADPH.

Question

Want to see the full answer?

Answer 1

Question

Chapter 20, Problem 31P

Interpretation Introduction

Interpretation:

The ratio of NADPH to NADP+ required to sustain given conditions should be determined.

Concept introduction:

Reduced glutathione (GSH) is a tripeptide with a sulfhydryl group. GSH reduces reactive oxygen species to harmless forms, thereby reducing the oxidative stress in the cell. This prevents the cell from various damages and cell death. When ROS are reduced, GSH is oxidized GSSG. In order to continue this ROS removal process GSH should be regenerated. So, GSSG is again reduced into GSH by NADPH.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Biochemistry What is the process of "transamination" in either the muscles or the liver, that involves keto acid or glutamic acid? Please explain how the steps work. Thank you!

Biochemistry Please help. Thank you What is the importance of glutamic acid in the metabolism of nitrogen from amino acids? (we know therole; it’s used to remove the nitrogen from amino acids so that the remaining carbon skeleton can bebroken down by the “usual” pathways, but what is the important, unique role that only glutamicacid/glutamate can do?)

Biochemistry Please help. Thank you When carbamyl phosphate is joined to L-ornathine, where does the energy for the reaction come from?