
To determine: The consequences if the transgene integrates randomly into the coding region, or the regulatory region, of an endogenous gene.
Introduction: Recombinant DNA (rDNA) technology has made it possible to directly manipulate genes in vivo using different techniques to learn more about gene function in living organisms. The modification of gene of interest and its reinsertion into an organism of the same species or a gene from an individual of one species is inserted into another species; these both approaches will result in the transgenic organism.
To determine: The reason due to which the random integration of the transgene into the coding region, or the regulatory region will complicate the genetic analysis of the transgene.
Introduction: Transgenics explains the technique of inserting foreign DNA into a host organism’s genome. In multicellular organisms, this technique can be performed by experimental manipulation of gametes or early embryos. It is very important that the vector containing transgene is incorporated into the target gene; otherwise, there will be dangerous consequences.

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Chapter 20 Solutions
Concepts of Genetics (12th Edition)
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