The transformation of the given compound to a primary amine using Gabriel synthesis is to be carried out. Concept introduction: A synthesis is a specific sequence of chemical reactions that converts starting materials into the desired compound, called the target (or synthetic target). Synthesis may be designed by thinking in the reverse direction, from the product to the starting compound, in a method called retrosynthesis. Retrosynthesis involves starting with the product and determining a suitable precursor from which it can be synthesized, without considering specific reactions. Gabriel synthesis is one of the important and effective ways of synthesis of a primary amine from an alkyl hailde. In Gabriel synthesis, the phthalimide is treated with strong base potassium hydroxide, followed by alkyl halide , to form primary amine as the final product.

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Chapter 20, Problem 20.8P

Interpretation Introduction

Interpretation:

The transformation of the given compound to a primary amine using Gabriel synthesis is to be carried out.

Concept introduction:

A synthesis is a specific sequence of chemical reactions that converts starting materials into the desired compound, called the target (or synthetic target). Synthesis may be designed by thinking in the reverse direction, from the product to the starting compound, in a method called retrosynthesis. Retrosynthesis involves starting with the product and determining a suitable precursor from which it can be synthesized, without considering specific reactions. Gabriel synthesis is one of the important and effective ways of synthesis of a primary amine from an alkyl hailde. In Gabriel synthesis, the phthalimide is treated with strong base potassium hydroxide, followed by alkyl halide, to form primary amine as the final product.

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