Chapter 20, Problem 20.8P

(a)

Interpretation Introduction

Interpretation:

Value of $m$ has to be calculated.

Concept Introduction:

Expression to compute $m$ is as follows:

  $m=\frac{\left(\text{Mean spike signal}-\text{Mean unspiked signal}\right)}{\left(0.50\text{ ppb}\right)}$

Here,

$m$ refers to slope.

(b)

Interpretation Introduction

Interpretation:

Signal detection limit has to be calculated.

Concept Introduction:

Expression to compute detection limit is as follows:

  $\text{Detection limit} =\frac{3s}{m}$

Here,

$m$ refers to slope.

$s$ denotes standard deviation for sample.

(c)

Interpretation Introduction

Interpretation:

Lower limit of quantitation has to be calculated.

Concept Introduction:

Formula to compute Lower limit of quantitation is as follows:

  $\text{Lower limit of quantitation}=\frac{10s}{m}$

Here,

$m$ refers to slope.

$s$ denotes standard deviation for sample.