Laboratory Manual for Microbiology Fundamentals: A Clinical Approach
Laboratory Manual for Microbiology Fundamentals: A Clinical Approach
3rd Edition
ISBN: 9781260163469
Author: OBENAUF, Steven
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 20, Problem 1Q
Summary Introduction

Introduction:

Infections occur due to an abnormal condition of body that disrupts important physical and physiological function of body. Disease is caused by improper diet, lack of exercise, various infectious agents that are present in nature, toxic substances, genetic disorders, and depression, stress that play role in illness and disturbs normal functioning of body.

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Answer to Problem 1Q

Correct answer:

Clostridium difficile is a most common cause of acute diarrhea and is associated with CDC due to its antibiotic resistance characteristics. Therefore, option (b) is correct.

Option (b) is given as “Clostridium difficile”.

Explanation of Solution

Justify reason for the correct statement:

There are some drug resistant pathogens are present in large intestine such as C.difficile. An antibiotic treatment may disrupt large intestine as antibiotic disturbs normal biota. Due to these bacteria produces two enterotoxins such as toxin A and B causes necrosis in intestinal walls and results in diarrhea as well as Clostridium difficile colitis. It is condition occurs in which inflammation occurs in colon.

Hence, option (b) is correct.

Justify reasons for the incorrect statements:

Option (a) is given as “Salmonella”.

It is found in the intestine of humans and animals. It causes infections through contaminated food and water. It is does not CDC. Hence, it is a wrong answer.

Option (c) is given as “Cryptosporidium”.

It is microscopic parasite that can cause diarrheal disease in humans. Hence, it is a wrong answer.

Option (d) is given as “Shigella.

It is bacteria which causes acute diarrhea in humans by ingestion of contaminated food and water. Hence, it is a wrong answer.

Hence, options (a), (c) and (d) are incorrect.

Conclusion

The bacteria Clostridium difficile  is resistant to antibiotics and may cause Clostridium difficile colitis in which inflammation occurs in colon.

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