Chapter 2, Problem 65P

a.

Summary Introduction

To determine: The condition of inheritance in the given diagram.

Introduction: Genetic abnormalities are those that occupy the chromosomal location and produce the non-functional proteins. The abnormalities can be caused due either to mutation in a single nucleotide or genes (from one to multiple) or due to transfer of an abnormal gene from parents.

b.

Summary Introduction

To determine: The probability of the first child to be diseased when person 1 and person 2 in the given pedigree get married.

Introduction: The gene transferred from parents may be dominant as well as the recessive. The expression of the genes or alleles determines the type of abnormalities in the progenies, which may be of four types, autosomal dominant and autosomal recessive, X-linked dominant and X-linked recessive.