Concepts of Genetics (11th Edition)
11th Edition
ISBN: 9780321948915
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 2, Problem 33ESP
An interesting procedure has been applied for assessing the chromosomal balance of potential secondary oocytes for use in human in vitro fertilization. Using fluorescence in situ hybridization (FISH), Kuliev and Verlinsky (2004) were able to identify individual chromosomes in first polar bodies and thereby infer the chromosomal makeup of “sister” oocytes. Assume that when examining a first polar body you saw that it had one copy (dyad) of each chromosome but two dyads of chromosome 21. What would you expect to be the chromosomal 21 complement in the secondary oocyte? What consequences are likely in the resulting zygote, if the secondary oocyte was fertilized?
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Kuliev and Verlinsky (2004) state that there was a relatively high number of separation errors at meiosis I. In these cases the centromere underwent a premature division, occurring at meiosis I rather than meiosis II. Regarding chromosome 21, what would you expect to be the chromosome 21 complement in the secondary oocyte in which you saw a single chromatid (monad) for chromosome 21 in the first polar body? If this secondary oocyte was involved in fertilization, what would be the expected consequences?
You are investigating two temperature-sensitive mutant cells. In one, you can inactivate shugoshin activity by raising the temperature slightly at the start of meiosis. In the other, you can similarly inactivate separase activity by raising the temperature. How would the two cells be affected by inactivating these proteins?
Based on the data in Table 1, which individual(s) is/are heterozygous? Select all that apply
a) B IV-8
b) C IV-3
c) B IV-9
d) A IV-3
Chapter 2 Solutions
Concepts of Genetics (11th Edition)
Ch. 2 - With the initial appearance of the feature we call...Ch. 2 - An organism has a diploid number of 16 in a...Ch. 2 - Examine Figure 2.12, which shows oogenesis in...Ch. 2 - Prob. 1CSCh. 2 - Prob. 2CSCh. 2 - Prob. 3CSCh. 2 - In this chapter, we focused on how chromosomes are...Ch. 2 - Review the Chapter Concepts list on page 14. All...Ch. 2 - What role do the following cellular components...Ch. 2 - Discuss the concepts of homologous chromosomes,...
Ch. 2 - If two chromosomes of a species are the same...Ch. 2 - Describe the events that characterize each stage...Ch. 2 - How are chromosomes named on the basis of their...Ch. 2 - Contrast telophase in plant and animal mitosis.Ch. 2 - Describe the phases of the cell cycle and the...Ch. 2 - Define and discuss these terms: (a) synapsis, (b)...Ch. 2 - Contrast the genetic content and the origin of...Ch. 2 - Given the end results of the two types of...Ch. 2 - Contrast spermatogenesis and oogenesis. What is...Ch. 2 - Explain why meiosis leads to significant genetic...Ch. 2 - A diploid cell contains three pairs of homologous...Ch. 2 - Considering Problem 15, predict the number of...Ch. 2 - During oogenesis in an animal species with a...Ch. 2 - What is the probability that, in an organism with...Ch. 2 - Prob. 19PDQCh. 2 - Describe the role of meiosis in the life cycle of...Ch. 2 - Contrast the chromatin fiber with the mitotic...Ch. 2 - Describe the folded-fiber model of the mitotic...Ch. 2 - Prob. 23PDQCh. 2 - If one follows 50 primary oocytes in an animal...Ch. 2 - The nuclear DNA content of a single sperm cell in...Ch. 2 - In mitosis, what chromatid combination(s) will be...Ch. 2 - During meiosis I, assuming no crossing over, what...Ch. 2 - Are there any possible combinations present during...Ch. 2 - Draw all possible combinations of chromatids...Ch. 2 - Assume that during meiosis I none of the C...Ch. 2 - Assume that each gamete resulting from Problem 29...Ch. 2 - A species of cereal rye (Secale cereale) has a...Ch. 2 - An interesting procedure has been applied for...Ch. 2 - Assume that you were examining a first polar body...Ch. 2 - Kuliev and Verlinsky (2004) state that there was a...
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- Somatic cells in organisms of a certain diploid plant species normally have 14 chromosomes. The chromosomes in the gametes are numbered from 1 through 7. Rarely, zygotes are formed that contain more or fewer than 14 chromosomes. A zygote that has the chromosome composition 111 22 33 44 555 66 77 is 1. A.) Anueploid or B.)Euploid , and its chromosome complement can be described as 2. A). trisomic , B.)allotriploid , C. autotriploid for chromosomes 1 and 5. Pick the correct letter for 1 and 2.arrow_forwardSelect the best process listed below for each of the following statements. Note that you need to know that the sequence of amino acids directly reflects the sequence of genes that coded for their placement. Homologous sets of genes ABCDEF and aBCdEF are located on - vnonhomologous chromosomes. Crossing over between them is suppressed because their locations are the result of this. Homologous sets of genes ABCDEF and AEDCBF are located on homologous chromosomes. A small region of a protein from three species is sequenced and found to be as follows: species X is alanine, glycine, glycine, threonine, alanine v species Y is alanine, glycine, threonine, alanine species Z is alanine, glycine, glycine, threonine, alanine The difference in the amino acid sequence of species Y is most likely due to this. a. Inversion b. Deletion A small region of a protein from three species is sequenced and found to be as follows: c. Gene duplication d. Translocation e. Insertion species X is alanine, glycine,…arrow_forwardConsider the following DNA molecule (shown in the picture) and assume this is the DNA sequence of the entire chromosomes. list the amino acid sequences of the possible protein or proteins that could be produced from this DNA sequence what would be the DNA sequence of a sister chromatid generated from this chromosome sequence? (specify the 5' nd 3' ends)arrow_forward
- In the following schematic drawing of a Holliday junction,one chromatid is shown in red, and the homologous chromatidis shown in blue. The red chromatid carries a dominant allelelabeled A and a recessive allele labeled b, whereas the blue chromatidcarries a recessive allele labeled a and a dominant allelelabeled B. Where would the DNA strands have to be cut to produce recombinantchromosomes? Would they be cut at sites 1 and 3, or at sites2 and 4? What would be the genotypes of the two recombinantchromosomes?arrow_forwardIn corn, male sterility is controlled by maternal cytoplasmic elements. This phenotype renders the male part of the corn plants (i.e the tassel) unable to produce fertile pollen; the female parts, however, remain receptive to pollination by pollen from male fertile corn plants. However, the presence of a nuclear fertility restorer gene F restores fertility to male sterile lines Using the cardboard chips, simulate the crosses indicated below. Give the genotypes and phenotypes of the offsprings in each cross, and properly label the nucleus and the cytoplasm of each individual in the cross Legend male sterile cytoplasm Male fertile cytoplasm FF nucleus Ff nucleus ff nucleus A. Male sterile female x FF male Explain the phenotype of the offspring B. Male sterile female x Ff male Explain the phenotype of the offspringarrow_forwardThe mutations called bobbed in Drosophila result from variable reductions (deletions) in the number of amplified genes coding for rRNA. Researchers trying to maintain bobbed stocks have often documented their tendency to revert to wild type in successive generations. Propose a mechanism based on meiotic recombination which could account for this reversion phenomenon. Why would wild-type flies become more prevalent in Drosophila cultures?arrow_forward
- The diagram below shows a cell during Meiosis II: a) What phase of Meiosis II is the cell in? How do you know? b) Assuming all of the chromosomes present during Meiosis II are shown in the figure above, how many chromosomes (counting homologous pairs as two chromosomes) does a gamete from this organism have? c) Draw the same cell during the same phase of Meiosis I. Label the elementsarrow_forwardConsider the first category of test-cross offspring shown in figure 8.2 (+b, LS). Consider also that the parents of the heterozygous female flies in the test cross had the following genotypes: bb, SS, and +, LL. A. What would be the physical phenotype of these flies? B. If PC was conducted with the DNA of one of these flies using the primers for the molecular marker, what would be the appearance of the bands on an electrophoresis gel with the PC products? C. If the gene for black body and the locus for the molecular marker (L long or S short) were unlinked, what proportion of the test-cross progeny would be black flies that are heterozygous for the molecular marker? What proportion would be flies with normal body color, which are homozygous for one form of the molecular marker? D. If the gene for black body and the locus for the molecular marker were linked, how would the proportion of flies be different?arrow_forwardGive typed explanationarrow_forward
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