The major product of the given reaction has to be given. Concept Introduction: Imidazoles are the aromatic compounds and also the heterocyclic ring of histidine. It exists in both protonated and non-protonated form at pH = 7.4 . Aromatic compounds such as benzene which is having closed ring and alternate double bonds undergo electrophilic aromatic substitution reactions. Electrophilic aromatic substitution takes place when an electrophile displaces a hydrogen atom of an aromatic ring. There are five most common electrophilic aromatic substitution reactions that are halogenation, nitration, sulfonation, Friedel-Crafts acylation and Friedel-Crafts alkylation. All these reactions take place by same two-step mechanism.

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Chapter 19.7, Problem 14P

Interpretation Introduction

Interpretation:

The major product of the given reaction has to be given.

Concept Introduction:

Imidazoles are the aromatic compounds and also the heterocyclic ring of histidine. It exists in both protonated and non-protonated form at pH=7.4. Aromatic compounds such as benzene which is having closed ring and alternate double bonds undergo electrophilic aromatic substitution reactions. Electrophilic aromatic substitution takes place when an electrophile displaces a hydrogen atom of an aromatic ring.

There are five most common electrophilic aromatic substitution reactions that are halogenation, nitration, sulfonation, Friedel-Crafts acylation and Friedel-Crafts alkylation. All these reactions take place by same two-step mechanism.

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