LaunchPad for Biology: How Life Works (Six-Months Online)
LaunchPad for Biology: How Life Works (Six-Months Online)
3rd Edition
ISBN: 9781319305727
Author: Morris, JAMES
Publisher: Macmillan Higher Education
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Chapter 19.4, Problem 11SAQ
Summary Introduction

The cis-regulatory elements are mostly composed of one or more binding sites for transcription factors. Some of which are function as activators and other repress the transcription. Thus, the transcription rate of a gene present in any kind of cell is identified by the transcription factor combination which existing in the cell. The combination of transcription factors in the cell to regulate the expression of a gene is called the combinatorial control.

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*Example 2: Tracing the path of an autosomal dominant trait Trait: Neurofibromatosis Forms of the trait: The dominant form is neurofibromatosis, caused by the production of an abnormal form of the protein neurofibromin. Affected individuals show spots of abnormal skin pigmentation and non-cancerous tumors that can interfere with the nervous system and cause blindness. Some tumors can convert to a cancerous form. i The recessive form is a normal protein - in other words, no neurofibromatosis.moovi A typical pedigree for a family that carries neurofibromatosis is shown below. Note that carriers are not indicated with half-colored shapes in this chart. Use the letter "N" to indicate the dominant neurofibromatosis allele, and the letter "n" for the normal allele. Nn nn nn 2 nn Nn A 3 N-
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