Genetics: Analysis and Principles
5th Edition
ISBN: 9780073525341
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 19.2, Problem 1COMQ
With regard to phage
provide a site where the phage can align with the E. coli chromosome and become inserted there.
attach the phage to the surface of the bacterium.
promote the movement of the phage from one bacterium to another.
facilitate the attachment of phage DNA to phage coat proteins.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 19 Solutions
Genetics: Analysis and Principles
Ch. 19.1 - 1. Homologous recombination refers to the exchange...Ch. 19.1 - During the molecular process of homologous...Ch. 19.1 - 3. A key difference between the original Holliday...Ch. 19.1 - Which of the following mechanisms can cause gene...Ch. 19.2 - With regard to phage , the role of attachment...Ch. 19.2 - 1. During site-specific recombination that occurs...Ch. 19.3 - Which of the following types of transposable...Ch. 19.3 - Prob. 2COMQCh. 19.3 - Prob. 3COMQCh. 19 - 1. Describe the similarities and differences...
Ch. 19 - Prob. 2CONQCh. 19 - 3. Which steps in the double-strand break model...Ch. 19 - Prob. 4CONQCh. 19 - Prob. 5CONQCh. 19 - Prob. 6CONQCh. 19 - Prob. 7CONQCh. 19 - 8. What is gene conversion?
Ch. 19 - Make a list of the differences between the...Ch. 19 - Prob. 10CONQCh. 19 - Prob. 11CONQCh. 19 - 12. According to the double-strand break model,...Ch. 19 - What type of DNA structure is recognized by RecG...Ch. 19 - Briefly describe three ways that antibody...Ch. 19 - 15. Describe the functions of the RAG1 and RAG2...Ch. 19 - According to the scenario shown in Figure 20.7,...Ch. 19 - Prob. 17CONQCh. 19 - Prob. 18CONQCh. 19 - Prob. 19CONQCh. 19 - 19. Why does transposition always produce direct...Ch. 19 - 20. Which types of TEs have the greatest potential...Ch. 19 - Prob. 22CONQCh. 19 - 22. Let’s suppose that a species of mosquito has...Ch. 19 - This chapter describes different types of TEs,...Ch. 19 - Prob. 25CONQCh. 19 - Prob. 29CONQCh. 19 - 26. What is the difference between an autonomous...Ch. 19 - Prob. 26CONQCh. 19 - Prob. 28CONQCh. 19 - 1. Briefly explain how McClintock determined that...Ch. 19 - Prob. 2EQCh. 19 - The work of McClintock showed that the presence of...Ch. 19 - 3. In your own words, explain the term transposon...Ch. 19 - Prob. 5EQCh. 19 - 5. Gerald Rubin and Allan Spradling devised a...Ch. 19 - Make a list of the similarities and differences...Ch. 19 - Prob. 2QSDCCh. 19 - Prob. 3QSDC
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