To comment: The quote from Warren Lewis (1922), “Were the various types of cells to lose their stickiness for one another and for the supporting extracellular matrix, our bodies would at once disintegrate and flow off into the ground in a mixed stream of cells”. Introduction : In most of the tissues, cell-cell adhesions are mediated by transmembrane proteins linked intracellularly with the cytoskeleton. They play an important role in maintaining the architecture of various tissues. Apart from cells, tissues also contain an extracellular matrix consisting of network of macromolecules. It provides physical support, binds cells together, and regulates their behavior.

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Chapter 19, Problem 5P

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To comment: The quote from Warren Lewis (1922), “Were the various types of cells to lose their stickiness for one another and for the supporting extracellular matrix, our bodies would at once disintegrate and flow off into the ground in a mixed stream of cells”.

Introduction: In most of the tissues, cell-cell adhesions are mediated by transmembrane proteins linked intracellularly with the cytoskeleton. They play an important role in maintaining the architecture of various tissues. Apart from cells, tissues also contain an extracellular matrix consisting of network of macromolecules. It provides physical support, binds cells together, and regulates their behavior.

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