The starting material required to synthesize the given compounds by acylation of enolate is to be provided. Concept introduction: The carbon–carbon bond forming reaction, useful for the synthesis of β − keto ester, is known as Claisen condensation reaction. In carbonyl condensation reaction, the enolate of one carbonyl compound reacts with the carbonyl group of another. The Claisen condensation between esters containing α-hydrogens, promoted by a base such as sodium ethoxide, affords β-ketoesters. The intramolecular version is known as Dieckmann Condensation. Claisen condensation is a reversible reaction.

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Answer 1

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Chapter 19, Problem 25P

Interpretation Introduction

Interpretation:

The starting material required to synthesize the given compounds by acylation of enolate is to be provided.

Concept introduction:

The carbon–carbon bond forming reaction, useful for the synthesis of β− keto ester, is known as Claisen condensation reaction.

In carbonyl condensation reaction, the enolate of one carbonyl compound reacts with the carbonyl group of another.

The Claisen condensation between esters containing α-hydrogens, promoted by a base such as sodium ethoxide, affords β-ketoesters.

The intramolecular version is known as Dieckmann Condensation.

Claisen condensation is a reversible reaction.

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Answer 2

Question

Chapter 19, Problem 25P

Interpretation Introduction

Interpretation:

The starting material required to synthesize the given compounds by acylation of enolate is to be provided.

Concept introduction:

The carbon–carbon bond forming reaction, useful for the synthesis of β− keto ester, is known as Claisen condensation reaction.

In carbonyl condensation reaction, the enolate of one carbonyl compound reacts with the carbonyl group of another.

The Claisen condensation between esters containing α-hydrogens, promoted by a base such as sodium ethoxide, affords β-ketoesters.

The intramolecular version is known as Dieckmann Condensation.

Claisen condensation is a reversible reaction.

Expert Solution & Answer

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Check out a sample textbook solution

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Answer 3

Question

Chapter 19, Problem 25P

Interpretation Introduction

Interpretation:

The starting material required to synthesize the given compounds by acylation of enolate is to be provided.

Concept introduction:

The carbon–carbon bond forming reaction, useful for the synthesis of β− keto ester, is known as Claisen condensation reaction.

In carbonyl condensation reaction, the enolate of one carbonyl compound reacts with the carbonyl group of another.

The Claisen condensation between esters containing α-hydrogens, promoted by a base such as sodium ethoxide, affords β-ketoesters.

The intramolecular version is known as Dieckmann Condensation.

Claisen condensation is a reversible reaction.

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Answer 4

Question

Chapter 19, Problem 25P

Interpretation Introduction

Interpretation:

The starting material required to synthesize the given compounds by acylation of enolate is to be provided.

Concept introduction:

The carbon–carbon bond forming reaction, useful for the synthesis of β− keto ester, is known as Claisen condensation reaction.

In carbonyl condensation reaction, the enolate of one carbonyl compound reacts with the carbonyl group of another.

The Claisen condensation between esters containing α-hydrogens, promoted by a base such as sodium ethoxide, affords β-ketoesters.

The intramolecular version is known as Dieckmann Condensation.

Claisen condensation is a reversible reaction.

Expert Solution & Answer

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Answer 5

Chapter 19, Problem 25P

Interpretation Introduction

Interpretation:

The starting material required to synthesize the given compounds by acylation of enolate is to be provided.

Concept introduction:

The carbon–carbon bond forming reaction, useful for the synthesis of β− keto ester, is known as Claisen condensation reaction.

In carbonyl condensation reaction, the enolate of one carbonyl compound reacts with the carbonyl group of another.

The Claisen condensation between esters containing α-hydrogens, promoted by a base such as sodium ethoxide, affords β-ketoesters.

The intramolecular version is known as Dieckmann Condensation.

Claisen condensation is a reversible reaction.

Answer 6

Chapter 19, Problem 25P

Interpretation Introduction

Interpretation:

The starting material required to synthesize the given compounds by acylation of enolate is to be provided.

Concept introduction:

The carbon–carbon bond forming reaction, useful for the synthesis of β− keto ester, is known as Claisen condensation reaction.

In carbonyl condensation reaction, the enolate of one carbonyl compound reacts with the carbonyl group of another.

The Claisen condensation between esters containing α-hydrogens, promoted by a base such as sodium ethoxide, affords β-ketoesters.

The intramolecular version is known as Dieckmann Condensation.

Claisen condensation is a reversible reaction.

Answer 7

Chapter 19, Problem 25P

Interpretation Introduction

Interpretation:

The starting material required to synthesize the given compounds by acylation of enolate is to be provided.

Concept introduction:

The carbon–carbon bond forming reaction, useful for the synthesis of β− keto ester, is known as Claisen condensation reaction.

In carbonyl condensation reaction, the enolate of one carbonyl compound reacts with the carbonyl group of another.

The Claisen condensation between esters containing α-hydrogens, promoted by a base such as sodium ethoxide, affords β-ketoesters.

The intramolecular version is known as Dieckmann Condensation.

Claisen condensation is a reversible reaction.

Answer 8

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Answer 11

Ch. 19 - PRACTICE PROBLEM 19.1 (a) Write a mechanism. for...Ch. 19 - Practice Problem 19.2 Since the products obtained...Ch. 19 - Prob. 3PP Ch. 19 - PRACTICE PROBLEM 19.4 Write mechanisms that...Ch. 19 - Prob. 5PP Ch. 19 - Prob. 6PP Ch. 19 - Practice Problem 19.7 The acid-catalyzed aldol...Ch. 19 - Prob. 8PP Ch. 19 - Practice Problem 19.9 (a) Provide a mechanism for...Ch. 19 - Prob. 10PP

Solution Summary: The author explains that the carbon–carbon bond forming reaction, useful for the synthesis of beta - keto ester, is called Claisen condensation reaction.

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Chapter 19 Solutions