Concepts of Genetics Plus Mastering Genetics with Pearson eText -- Access Card Package (12th Edition) (What's New in Genetics)
12th Edition
ISBN: 9780134811390
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Videos
Textbook Question
Chapter 19, Problem 21ESP
Prader–Willi syndrome (PWS) is a genetic disorder with a clinical profile of obesity, intellectual disability, and short stature. It can be caused in several ways. Most common is a deletion on the paternal copy of chromosome 15, but it can also be caused by an epigenetic imprinting disorder, and uniparental disomy, an event in which the affected child receives two copies of the maternal chromosome 15. A child with PWS comes to your clinic for a diagnosis of the molecular basis for this condition. The gel below shows the results of testing with short tandem repeats (STRs) from the region of chromosome 15 associated with the disorder.
- (a) Is this case caused by a deletion in the paternal copy of chromosome 15? Explain.
- (b) Based on your interpretation of the data, what is the cause of PWS in this case? Explain your reasoning.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
One of the ways for a cell to generate ATP is through the oxidative phosphorylation. In oxidative phosphorylation 3 ATP are produced from every one NADH molecule. In respiration, every glucose molecule produces 10 NADH molecules. If a cell is growing on 5 glucose molecules, how much ATP can be produced using oxidative phosphorylation/aerobic respiration?
If a cell is growing on 5 glucose molecules, how much ATP can be produced using oxidative phosphorylation/aerobic respiration?
How do i know which way the arrows go?
Chapter 19 Solutions
Concepts of Genetics Plus Mastering Genetics with Pearson eText -- Access Card Package (12th Edition) (What's New in Genetics)
Ch. 19 - Although histone modifications can activate or...Ch. 19 - Prob. 2NSTCh. 19 - Prob. 1CSCh. 19 - Prob. 2CSCh. 19 - A couple well informed about the epigenetic...Ch. 19 - Prob. 1PDQCh. 19 - Prob. 2PDQCh. 19 - Prob. 3PDQCh. 19 - Prob. 4PDQCh. 19 - Prob. 5PDQ
Ch. 19 - Prob. 6PDQCh. 19 - Prob. 7PDQCh. 19 - Prob. 8PDQCh. 19 - Prob. 9PDQCh. 19 - Prob. 10PDQCh. 19 - What are the functions of IncRNAs in epigenetic...Ch. 19 - Prob. 12PDQCh. 19 - What are the differences and similarities among...Ch. 19 - Prob. 14PDQCh. 19 - Prob. 15PDQCh. 19 - Should fertility clinics be required by law to...Ch. 19 - Prob. 17PDQCh. 19 - Prob. 18PDQCh. 19 - A developmental disorder in humans called spina...Ch. 19 - Prob. 20PDQCh. 19 - PraderWilli syndrome (PWS) is a genetic disorder...Ch. 19 - Prob. 22ESPCh. 19 - Prob. 23ESPCh. 19 - Methylation of H3K9 by itself silences genes, but...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Identify the indicated structure (Saprolegnia). a. antheridium O b. oospore c.sperm d. auxospore e. tetraspore Of. zygosporearrow_forwardUsing information from the primary literature (several references have been provided as a starting point below) please answer the following question: Based on your review of the literature on rewilding, what are the major scientific pros and cons for rewilding? Please note that the focus of this assignment are the (biological) scientific issues associated with rewilding. As will be discussed in class, there are a number of non-scientific issues involved or implicated in rewilding, all ultimately affecting the public acceptability of rewilding. Although these issues are important – indeed, critical – in this assignment you should focus on the biological science issues and questions. Details: You must enumerate at least two pros and at least two cons. Your answer should be no more than 500 well-chosen words, excluding references. Think carefully about how best to organize and structure your answer. Aim for high information density: say a lot, but say it succinctly. Recall Nietzche’s…arrow_forwardUsing information from the primary literature (several references have been provided as a starting point below) please answer the following question: Based on your review of the literature on rewilding, what are the major scientific pros and cons for rewilding? Please note that the focus of this assignment are the (biological) scientific issues associated with rewilding. As will be discussed in class, there are a number of non-scientific issues involved or implicated in rewilding, all ultimately affecting the public acceptability of rewilding. Although these issues are important – indeed, critical – in this assignment you should focus on the biological science issues and questions. Details: You must enumerate at least two pros and at least two cons. Your answer should be no more than 500 well-chosen words, excluding references. Think carefully about how best to organize and structure your answer. Aim for high information density: say a lot, but say it succinctly. Recall Nietzche’s…arrow_forward
- Now draw a rough sketch of what the control data might look like if in addition to the specific binding, there was also a considerable amount of nonspecific binding (again using a normal dose/response curve) (do % total bound ligand vs concentration)arrow_forwardWhat are functions of cuboidal cells in the kidney? Select all that apply. Concentration of gases Dilution of chemicals Secretion of molecules Nutrition to tissues Support of tissues Absorption of moleculesarrow_forwardquestion1 In plants, epithelial tissue is only found as the outermost cell layer and acts as a barrier. In humans, epithelial tissue is found inside the body as well as on the surface. What function(s) does/do epithelial tissue carry out in humans? Select all that apply. Waste storage Filtration Oxygen transport Protection Diffusion Osmosis Absorptionarrow_forward
- What words best describes this organism? a. Unicellular/nonmotile Ob. unicellular/motile c. colonial/nonmotile d. colonial/motile e. multicelluar O f. siphonous g. none of thesearrow_forwardIdentify the phylum or class. a. Euglenophyta b. Dinoflagellata c. Bacillariophyceae d. Oomycetes e. Phaeophyceae O f. Myxomycota g. Xanthophyceae ○ h. Chrysophyceae i. Dictyosteliomycota O j. Rhodophyta Ok. Chlorophyceaens I. Charophyceaensarrow_forwardWhat is produced inside the indicated structure (Fucus). a. eggs O b. antheridia ○ c. sperm d. zygotes e. none of thesearrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Biology Today and Tomorrow without Physiology (Mi...BiologyISBN:9781305117396Author:Cecie Starr, Christine Evers, Lisa StarrPublisher:Cengage Learning
Human Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage Learning
Biology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Biology Today and Tomorrow without Physiology (Mi...
Biology
ISBN:9781305117396
Author:Cecie Starr, Christine Evers, Lisa Starr
Publisher:Cengage Learning
Human Biology (MindTap Course List)
Biology
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cengage Learning
Biology (MindTap Course List)
Biology
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Cengage Learning
What are Mutations and what are the different types of Mutations?; Author: Science ABC;https://www.youtube.com/watch?v=I16YlE8qTBU;License: Standard youtube license