
During development, cells become
a. differentiated before they become determined.
b. determined before they become differentiated.
c. determined by the loss of genetic material.
d. differentiated by the loss of genetic material.

Introduction:
When an undifferentiated cell divides, it doesn’t differentiate immediately. It decides its fate before following the decision. This decision making is termed as determination. A determined cell differentiates into the cell it was determined to be.
Answer to Problem 1U
Correct answer:
A cell always determines before differentiating into a specific cell. Therefore, option b. is correct.
Explanation of Solution
Reason for the correct statement:
A cell can’t commit to a particular differentiation as soon as it divides. It first determines its fate, then it commits to be a particular cell. Moreover, a determined cell might change its fate and differentiate into a different cell type positional signaling.
Option b. is given as “determined before they become differentiated”.
As “during development, cells become determined before they become differentiated”, it is the right answer.
Hence, option b. is correct.
Reasons for the incorrect statements:
Option a. is given as “differentiated before they become determined”.
Cells first determine then differentiate not the other way around. So, it is a wrong answer.
Option c. is given as “determined by the loss of genetic material”.
The genetic loss can’t help in the determination and development of a cell. So, it is a wrong answer.
Option d. is given as “differentiated by the loss of genetic material”.
The genetic loss can’t help in the differentiation and development of a cell. So, it is a wrong answer.
Hence, options a., c., and d. are incorrect.
A cell first determines than differentiates during the course of development.
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Chapter 19 Solutions
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