FUNDAMENTALS OF ANATOMY AND PHYSIOLOGY
FUNDAMENTALS OF ANATOMY AND PHYSIOLOGY
11th Edition
ISBN: 2818440070945
Author: Martini
Publisher: PEARSON C
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Chapter 19, Problem 1CC
Summary Introduction

To determine:

The reason for the pain in Clare’s body.

Introduction:

Sickle cell disease or SCD is a disease in which the RBCs of the blood are not cup shaped, but are sickle shaped. This disease helped in preventing the malarial parasite from completing its reproductive cycle. This disease is caused by the genetic mutation of the hemoglobin gene that cause deformed RBCs production.

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*Example 2: Tracing the path of an autosomal dominant trait Trait: Neurofibromatosis Forms of the trait: The dominant form is neurofibromatosis, caused by the production of an abnormal form of the protein neurofibromin. Affected individuals show spots of abnormal skin pigmentation and non-cancerous tumors that can interfere with the nervous system and cause blindness. Some tumors can convert to a cancerous form. i The recessive form is a normal protein - in other words, no neurofibromatosis.moovi A typical pedigree for a family that carries neurofibromatosis is shown below. Note that carriers are not indicated with half-colored shapes in this chart. Use the letter "N" to indicate the dominant neurofibromatosis allele, and the letter "n" for the normal allele. Nn nn nn 2 nn Nn A 3 N-
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