Campbell Biology, Books a la Carte Plus Mastering Biology with eText -- Access Card Package (10th Edition)
10th Edition
ISBN: 9780133922851
Author: Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson
Publisher: PEARSON
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Chapter 19, Problem 19.2CR
Summary Introduction
To determine: The enzymes that are essential for certain types of viruses for the replication but not found in normal cells.
Introduction: Viruses are microscopic organisms that can replicate only inside a host. They cannot remain outside a host cell. The virus uses replication machinery from the host to produce its progeny.
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You are studying a new retrovirus. The viral protein (X) appears to play a role in the export of the viral genomes to the
cytoplasm. Protein X brings viral DNA to the cytoplasm and returns back to the nucleus after genome export is complete.
Researchers have developed a new drug for the virus. Following treatment with the new drug, the viral protein stays in the
nucleus and cannot export the viral genomes. What is the most plausible and logical function of the drug? Use your
knowledge of nuclear transport to answer this question.
O A. The drug inhibits the binding of the viral protein and the viral genomes to the import receptor.
B. The drug inhibits the binding of Ran-GTP to the nuclear export receptor in nucleus.
C. The drug promotes the Ran GAP activity.
D. The drug blocks the NLS on the viral protein.
If a viral host cell has a mutation that interferes with the addition of carbohydrates to proteins (glycoproteins) during processing in the Golgi
apparatus, which of the following processes is most likely to occur?
O A. Viruses released by that host cell would have a decreased ability to infect cells than the virus that originally infected the cell.
B. The virus-encoded protease would be unable to cleave large viral proteins into smaller, functional polypeptides.
OC. The virus would be unable to replicate within the host cell.
D. Viruses released by that cell are novel and would result in infections with higher mortality rates.
Explain the processes involved in viral replication or virus reproduction.
Chapter 19 Solutions
Campbell Biology, Books a la Carte Plus Mastering Biology with eText -- Access Card Package (10th Edition)
Ch. 19.1 - Prob. 1CCCh. 19.1 - MAKE CONNECTIONS Bacteriophages were used to...Ch. 19.2 - Compare the effect on the host cell of a lytic...Ch. 19.2 - Prob. 2CCCh. 19.2 - Why is HIV called a retrovirus?Ch. 19.2 - Prob. 4CCCh. 19.3 - Describe two ways in which a preexisting virus can...Ch. 19.3 - Contrast horizontal and vertical transmission of...Ch. 19.3 - WHAT IF? TMV has been isolated from virtually all...Ch. 19 - Are viruses generally considered living or...
Ch. 19 - Prob. 19.2CRCh. 19 - Prob. 19.3CRCh. 19 - Which of the following characteristics,...Ch. 19 - Emerging viruses arise by (A) mutation of existing...Ch. 19 - Prob. 3TYUCh. 19 - Prob. 4TYUCh. 19 - Prob. 5TYUCh. 19 - Prob. 6TYUCh. 19 - EVOLUTION CONNECTION The successof some viruses...Ch. 19 - SCIENTIFIC INQUIRY When bacteria infect an animal,...Ch. 19 - WRITE ABOUT A THEME: ORGANIZATION While viruses...Ch. 19 - Prob. 10TYU
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- Viruses are made up of the same biomolecules as cellular organisms (DNA, RNA, proteins, lipids, etc.). They infect cells and replicate themselves using resources from the host cells. Scientists discovered a previously unknown strain of virus in the tropical Pacific Ocean and it can infect higher-order eukaryotes. Initial analysis revealed that the virus is mainly composed of nucleic acids, proteins, and lipids. Chemical analysis after complete hydrolysis revealed the following building blocks (by weight): Chemical components Nucleosides Amino acids Lipids, phosphates, and carbohydrates Percentage by weight 20 30 50 Analysis of percentages of nucleosides yielded the following results (by molar ratio): Nucleosides A G T C U Percentage by mole 19 29 19 29 4 Researchers determined that the lipids found in the virus form a bilayer membrane surrounding the virus, and are obtained from the membrane of the host cell during virus maturation and exit from host cell. Further…arrow_forwardContrast the enzyme(s) used by retroviruses and positive strand RNA viruses to complete their lifecycles.arrow_forwardAs a general rule, viruses are not considered to be alive based on several reasons. One such reason is that some viruses use RNA as their genetic material instead of DNA. Which of the five biological themes does this violate? Briefly explain why.arrow_forward
- List the step common to all viral replication pathways.arrow_forwardIn a [1] infection, the viral DNA is inserted into the host cells DNA. it remains there and is copied each time the cell multiplies.arrow_forwardBriefly describe the two approaches a bacteriophagecan take to trigger an infection once inside its host cell.arrow_forward
- Which of the following is a known characteristic or procesds that can lead to genetic changes in some viruses? When two different viral strains of the same type of virus infect a single individual, reassortment/mixing of segmented genome pieces can occur, resulting in new combinations of segments. Genetic rearrangements of the viral genome occurs as a result of duplicate operons in the viral genome undergoing homologous recombination. Environmental conditions trigger the SOS response in viruses, and leads to generation of errors/mutations in the viral genome. Viral RNA polymerases display proofreading capability in replicating the viral genome of certain viruses.arrow_forwardDefine prion.arrow_forwardExplain the lytic cycle of a bacteriophages life cycle.arrow_forward
- The second step in viral replication is entry. For bacteriophage, entry usually involves: O a) direct entry of the nucleic acid into the cell. Ob) phagocytosis. c) membrane fusion mechanism of entry. d) receptor-mediated endocytosis.arrow_forwardExplain why a virus is considered living or not living?arrow_forwardWhich of the following is NOT true regarding the genetic code and translation? a) An mRNA is typically translated in only 1 reading frame. b) There are 64 different codons. c) Multiple amino acids may be coded for by a single codon. d) mRNA sequence is the reverse complement of the template strand of DNA.arrow_forward
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