Chapter 18.5, Problem 6AYLO

Summary Introduction

To discuss:

The intrinsic mechanism of blood coagulation, the factor initiating it, other procoagulants in the mechanism, and the common point of convergence with the extrinsic mechanism.

Introduction:

Blood coagulation takes place as two distinct reaction pathways, namely the extrinsic pathway and the intrinsic pathway, both of which require various factors from beginning to end and involve around 30 chemical reactions. In the intrinsic pathway, factors within the blood are involved, whereas in the extrinsic pathway, the involved factors are present outside the blood.