To suggest: How XIST RNA initiates the formation of the Barr body. Introduction: Female mammals inherit two X chromosomes and one of them is inactivated during embryonic development by the XIST gene. This is known as the dosage compensation mechanism, allowing both males and females to have one active X chromosome. This inactivated X chromosome condenses and forms the Barr body due to changes in DNA and histone proteins.

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Chapter 18.3, Problem 3CC

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To suggest: How XIST RNA initiates the formation of the Barr body.

Introduction:

Female mammals inherit two X chromosomes and one of them is inactivated during embryonic development by the XIST gene. This is known as the dosage compensation mechanism, allowing both males and females to have one active X chromosome. This inactivated X chromosome condenses and forms the Barr body due to changes in DNA and histone proteins.

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