The synthesis of anisole has to be illustrated using benzene as the starting compound. Concept Introduction: Benzene is a stable aromatic compound and it is the simplest form of the aromatic compounds . It is a very versatile compound that it furnishes various products with various reagents. The most common type of reactions that benzene undergoes is electrophilic substitution reactions. The various types of electrophilic substitution reactions in benzene are – Chlorination, Bromination, Nitration, Sulfonation, Friedel Crafts Alkylation/Acylation etc. So it is clear benzene can be converted to various range of compounds with appropriate reagents and reaction conditions. One of the useful method one can adapt to introduce any kind of group or atom onto the benzene ring is electrophilic substitution reaction. Aromatic compounds undergo another type of reactions called elimination – addition reaction. A compound with leaving group when treated with a strong base under high or low temperature undergoes elimination – addition reaction where the leaving group is eliminated and a new group is added. Halogens are known to be best leaving groups.

Question

Want to see the full answer?

Answer 1

Question

Chapter 18.14, Problem 34CC

Interpretation Introduction

Interpretation:

The synthesis of anisole has to be illustrated using benzene as the starting compound.

Concept Introduction:

Benzene is a stable aromatic compound and it is the simplest form of the aromatic compounds. It is a very versatile compound that it furnishes various products with various reagents.

The most common type of reactions that benzene undergoes is electrophilic substitution reactions.

The various types of electrophilic substitution reactions in benzene are – Chlorination, Bromination, Nitration, Sulfonation, Friedel Crafts Alkylation/Acylation etc.

So it is clear benzene can be converted to various range of compounds with appropriate reagents and reaction conditions. One of the useful method one can adapt to introduce any kind of group or atom onto the benzene ring is electrophilic substitution reaction.

Aromatic compounds undergo another type of reactions called elimination – addition reaction. A compound with leaving group when treated with a strong base under high or low temperature undergoes elimination – addition reaction where the leaving group is eliminated and a new group is added. Halogens are known to be best leaving groups.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

The following intermediates are to proceed by acetoacetic ester synthesis. What are intermediates 1 and 2 plus the final product 3? Please include a detailed explanation and drawings of the intermediates and how they occurred.

What are the missing intermediates 1, 2, and 3? Please include a detailed explanation explaining the steps of malonic ester synthesis. Please include drawings of the intermediates and how they occur.

What is the reactant that makes the following product of the reaction? Please provide a detailed explanation and a drawing to show how the reaction proceeds.