Campbell Biology (11th Edition)
11th Edition
ISBN: 9780134093413
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Publisher: PEARSON
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Textbook Question
Chapter 18.1, Problem 1CC
How does binding of the trp corepressor to the trp repressor alter repressor function and transcription? What about the binding of the lac inducer to the lac repressor?
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How are the actions of lac repressor and trp repressor similar and how are they different with regard to their binding to operator sites, their effects on transcription, and the influences of small effector molecules?
Which of the following is the most likely result of a mutation in the lac operator that prevents release of the depressor protein?
Choose 1 answer:
(A)The lactose permease protein will be produced, even in the absence of lactose.
(B) Transcription of the structural genes will be blocked, even in the presence of lactose.
(C) The catabolite activator protein will be bound to the CAP site, even in the presence of glucose.
(D) Expression of the lacI gene will be repressed, even in the absence of glucose.
How does the repressor protein contribute to selective expression of the structural genes Z, Y, and A in the lac operon?
The repressor protein is only expressed when lactose is present.
The repressor is always expressed. It blocks transcription when lactose is present.
The repressor is always expressed. It allows transcription when lactose is absent.
The repressor is always expressed. It blocks transcription when lactose is absent.
The repressor protein is only expressed when lactose is absent.
Chapter 18 Solutions
Campbell Biology (11th Edition)
Ch. 18.1 - How does binding of the trp corepressor to the trp...Ch. 18.1 - Describe the binding of RNA Polymerase,...Ch. 18.1 - WHAT IF? A certain mutation in E. coli changes...Ch. 18.2 - In general, what are the effects of histone...Ch. 18.2 - MAKE CONNECTIONS Speculate about whether the same...Ch. 18.2 - Compare the roles of general and specific...Ch. 18.2 - Once mRNA encoding a particular protein reaches...Ch. 18.2 - WHAT IF? Suppose you compared the nucleotide...Ch. 18.3 - Compare miRNAs and siRNAs, including their...Ch. 18.3 - WH AT IF? Suppose the mRNA being degraded in...
Ch. 18.3 - MAKE CONNECTIONS Inactivation of one of the X...Ch. 18.4 - MAKE CONNECTIONS As you learned in Chapter 12,...Ch. 18.4 - MAKE CONNECTIONS Explain how the signaling...Ch. 18.4 - How do fruit fly maternal effect genes determine...Ch. 18.4 - Prob. 4CCCh. 18.5 - Prob. 1CCCh. 18.5 - Under what circumstances is cancer considered to...Ch. 18.5 - MAKE CONNECTIONS The p53 protein can activate...Ch. 18 - Compare and contrast the roles of a corepressor...Ch. 18 - Describe what must happen in a cell for a gene...Ch. 18 - Why are miRNAs called noncoding RNAs? Explsin how...Ch. 18 - Describe the two main processes that cause...Ch. 18 - Compare the usual functions of proteins encoded by...Ch. 18 - If a particular operon encodes enzymes for making...Ch. 18 - Muscle cells differ from nerve cells mainly...Ch. 18 - The functioning of enhancers is an example of (A)...Ch. 18 - Cell differentiation always involves (A)...Ch. 18 - Which of the following is an example of...Ch. 18 - What would occur if the repressor of an inducible...Ch. 18 - Absence of bicoid in mRNA from a Drosophila egg...Ch. 18 - Which of the following statements about the DNA in...Ch. 18 - Within a cell, the amount of protein made using a...Ch. 18 - Prob. 10TYUCh. 18 - draw it The diagram below shows five genes,...Ch. 18 - Prob. 12TYUCh. 18 - Prob. 13TYUCh. 18 - SCIENCE. TECHNOLOGY, AND SOCIETY Trace amounts of...Ch. 18 - WRITE ABOUT A THEME: INTERACTIONS In a Short essay...Ch. 18 - SYNTHESIZE YOUR KNOWLEDGE The flashlight fish has...
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- How could the expression of Lactase RNA be turned on and off by transcription factors, activators, and repressors?arrow_forwardWhat are general transcription factors? When do you expect to find them? What is a cis acting regulatory sequence? Where are they located in comparison with the gene they are regulating?arrow_forwardA mutation in the trp repressor gene that prevents the apo-repressor from binding the co-repressor What is the correct option from the choices below? causes the Trp repressor to permanently bind the trp operator. leads to a high level of transcription initiation from the trp promoter, even when tryptophan is present in the medium. does not lead to a high concentration of mRNA molecules that code for the structural genes trp E, D, C, B, A, when tryptophan is present in the medium, because attenuation of the operon will still work. a and b, but not c b and c, but not aarrow_forward
- When CAMP binds to the Catabolite Activator Protein (CAP), it causes a conformational change on the protein, which results in binding to the CAP- binding site on the DNA and molecule is known as a(n) of the lac operon. This conformational change induced by the binding of another transcription activation; allosteric effect transcription repression; binding effect translation; distortion effect mutation; interactive effect attenuation; compression effect O O O Oarrow_forwardIf the lacZ protein breaks down lactose, is it worthwhile to make it when there is no lactose around? How does the bacteria use this system to efficiently control the production of the lacZ protein? Does the presence of lactose in the cell alter its ability to repress translation? To what does the lacI protein bind to? What effect does the lacI gene have on transcription of the lacZ and lacY genes?arrow_forwardWhat is the difference between a general transcription factor (like sigma 70) and a regulatory transcription factor (like lac repressor)? Compare and contrast their roles in regulating RNA polymerase and in regulating transcription.arrow_forward
- What is a positive effect of proteasome proteins being associated with transcription?arrow_forwardSome compounds called antiinducers bind to repressors such as the lac repressor and inhibit the action of inducers; that is, transcription is repressed and higher concentrations of inducer are required to induce transcription. Propose a mechanism of action for anti-inducers.arrow_forwardIf the lacl gene is mutated so that the repressor protein no longer binds to lactose, what will be the effect on the expression of B-galactosidase in lactose's presence and absence? Explain. If the promoter for lacl is mutated so that the expression of the repressor increases, what will be the effect on the expression of B-galactosidase in the presence and absence of lactose? Explain. D. (Extremely tricky question!) Describe the behavior of the lac operon assuming that the lacl gene has been mutated so that the repressor now binds to DNA in the presence of lactose but cannot bind to DNA in the absence of lactose.arrow_forward
- How would a mutation which prevented Gal3 from binding to Gal80 affect gene expression from the GAL promoter?arrow_forwardExamine Figure 17.7. What would be the effect on transcription if a mutation occurred in the gene that encodes GAL3, so that no functional GAL3 was produced?arrow_forwardWhy does histone deacetylase action tend to repress transcription?arrow_forward
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