The features of dynactin complex which helps dynein to transport cargo towards the microtubules. Also, we need to know the effect of inhibition of dynactin + TIP EB1 has on the orientation of the spindle. Introduction: The motor proteins Kinesin and Dynein are part of the same family of proteins which constitute the cytoskeletal system. These proteins are mainly responsible for cellular movement based on direction and location. ATP also helps in the cell movement. Both these proteins have MTOCs in the cell. Dynein molecule has two heads and it has very high mechanical energy. Kinesin-2 is a heterometric compound having two major chains and one binding subunit. Studies show that Kinesin-2 is needed for dispersion of granules and dynein is necessary for aggregation. Hence both Kinesin-2 and Dynein coordinate to make a proper motion of granules. This mechanism is common to most of the cells like Melanosomes, Endosomes, Mitochondria etc.

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Answer 1

Question

Chapter 18, Problem 9RTC

Summary Introduction

To write:

The features of dynactin complex which helps dynein to transport cargo towards the microtubules. Also, we need to know the effect of inhibition of dynactin + TIP EB1 has on the orientation of the spindle.

Introduction:

The motor proteins Kinesin and Dynein are part of the same family of proteins which constitute the cytoskeletal system. These proteins are mainly responsible for cellular movement based on direction and location. ATP also helps in the cell movement. Both these proteins have MTOCs in the cell. Dynein molecule has two heads and it has very high mechanical energy.

Kinesin-2 is a heterometric compound having two major chains and one binding subunit. Studies show that Kinesin-2 is needed for dispersion of granules and dynein is necessary for aggregation. Hence both Kinesin-2 and Dynein coordinate to make a proper motion of granules. This mechanism is common to most of the cells like Melanosomes, Endosomes, Mitochondria etc.

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Answer 2

Question

Chapter 18, Problem 9RTC

Summary Introduction

To write:

The features of dynactin complex which helps dynein to transport cargo towards the microtubules. Also, we need to know the effect of inhibition of dynactin + TIP EB1 has on the orientation of the spindle.

Introduction:

The motor proteins Kinesin and Dynein are part of the same family of proteins which constitute the cytoskeletal system. These proteins are mainly responsible for cellular movement based on direction and location. ATP also helps in the cell movement. Both these proteins have MTOCs in the cell. Dynein molecule has two heads and it has very high mechanical energy.

Kinesin-2 is a heterometric compound having two major chains and one binding subunit. Studies show that Kinesin-2 is needed for dispersion of granules and dynein is necessary for aggregation. Hence both Kinesin-2 and Dynein coordinate to make a proper motion of granules. This mechanism is common to most of the cells like Melanosomes, Endosomes, Mitochondria etc.

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Answer 3

Question

Chapter 18, Problem 9RTC

Summary Introduction

To write:

The features of dynactin complex which helps dynein to transport cargo towards the microtubules. Also, we need to know the effect of inhibition of dynactin + TIP EB1 has on the orientation of the spindle.

Introduction:

The motor proteins Kinesin and Dynein are part of the same family of proteins which constitute the cytoskeletal system. These proteins are mainly responsible for cellular movement based on direction and location. ATP also helps in the cell movement. Both these proteins have MTOCs in the cell. Dynein molecule has two heads and it has very high mechanical energy.

Kinesin-2 is a heterometric compound having two major chains and one binding subunit. Studies show that Kinesin-2 is needed for dispersion of granules and dynein is necessary for aggregation. Hence both Kinesin-2 and Dynein coordinate to make a proper motion of granules. This mechanism is common to most of the cells like Melanosomes, Endosomes, Mitochondria etc.

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Answer 4

Question

Chapter 18, Problem 9RTC

Summary Introduction

To write:

The features of dynactin complex which helps dynein to transport cargo towards the microtubules. Also, we need to know the effect of inhibition of dynactin + TIP EB1 has on the orientation of the spindle.

Introduction:

The motor proteins Kinesin and Dynein are part of the same family of proteins which constitute the cytoskeletal system. These proteins are mainly responsible for cellular movement based on direction and location. ATP also helps in the cell movement. Both these proteins have MTOCs in the cell. Dynein molecule has two heads and it has very high mechanical energy.

Kinesin-2 is a heterometric compound having two major chains and one binding subunit. Studies show that Kinesin-2 is needed for dispersion of granules and dynein is necessary for aggregation. Hence both Kinesin-2 and Dynein coordinate to make a proper motion of granules. This mechanism is common to most of the cells like Melanosomes, Endosomes, Mitochondria etc.

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Answer 5

Chapter 18, Problem 9RTC

Summary Introduction

To write:

The features of dynactin complex which helps dynein to transport cargo towards the microtubules. Also, we need to know the effect of inhibition of dynactin + TIP EB1 has on the orientation of the spindle.

Introduction:

The motor proteins Kinesin and Dynein are part of the same family of proteins which constitute the cytoskeletal system. These proteins are mainly responsible for cellular movement based on direction and location. ATP also helps in the cell movement. Both these proteins have MTOCs in the cell. Dynein molecule has two heads and it has very high mechanical energy.

Kinesin-2 is a heterometric compound having two major chains and one binding subunit. Studies show that Kinesin-2 is needed for dispersion of granules and dynein is necessary for aggregation. Hence both Kinesin-2 and Dynein coordinate to make a proper motion of granules. This mechanism is common to most of the cells like Melanosomes, Endosomes, Mitochondria etc.

Answer 6

Chapter 18, Problem 9RTC

Summary Introduction

To write:

The features of dynactin complex which helps dynein to transport cargo towards the microtubules. Also, we need to know the effect of inhibition of dynactin + TIP EB1 has on the orientation of the spindle.

Introduction:

The motor proteins Kinesin and Dynein are part of the same family of proteins which constitute the cytoskeletal system. These proteins are mainly responsible for cellular movement based on direction and location. ATP also helps in the cell movement. Both these proteins have MTOCs in the cell. Dynein molecule has two heads and it has very high mechanical energy.

Kinesin-2 is a heterometric compound having two major chains and one binding subunit. Studies show that Kinesin-2 is needed for dispersion of granules and dynein is necessary for aggregation. Hence both Kinesin-2 and Dynein coordinate to make a proper motion of granules. This mechanism is common to most of the cells like Melanosomes, Endosomes, Mitochondria etc.

Answer 7

Chapter 18, Problem 9RTC

Summary Introduction

To write:

The features of dynactin complex which helps dynein to transport cargo towards the microtubules. Also, we need to know the effect of inhibition of dynactin + TIP EB1 has on the orientation of the spindle.

Introduction:

The motor proteins Kinesin and Dynein are part of the same family of proteins which constitute the cytoskeletal system. These proteins are mainly responsible for cellular movement based on direction and location. ATP also helps in the cell movement. Both these proteins have MTOCs in the cell. Dynein molecule has two heads and it has very high mechanical energy.

Kinesin-2 is a heterometric compound having two major chains and one binding subunit. Studies show that Kinesin-2 is needed for dispersion of granules and dynein is necessary for aggregation. Hence both Kinesin-2 and Dynein coordinate to make a proper motion of granules. This mechanism is common to most of the cells like Melanosomes, Endosomes, Mitochondria etc.

Answer 8

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Ch. 18 - Prob. 1RTC Ch. 18 - Prob. 2RTC Ch. 18 - Prob. 3RTC Ch. 18 - Prob. 4RTC Ch. 18 - Prob. 5RTC Ch. 18 - Prob. 6RTC Ch. 18 - Prob. 7RTC Ch. 18 - Prob. 8RTC Ch. 18 - Prob. 9RTC Ch. 18 - Prob. 10RTC

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