Least reactive compound under Friedel–Craft condition has to be identified among the given compounds. Concept Introduction: Friedel-Crafts Alkylation: This Lewis acid-catalyzed electrophilic aromatic replacement allows the synthesis of alkylated products by means of the reaction of arenes through alkyl halides. Electrophilic substitution reaction is a type of reaction in which a particular group or atom in a compound is replaced by electrophile. An electrophile is a species that is deficient of electrons Deactivators are electron withdrawing groups attached to the benzenes that have either positive charge or an atom with high electronegativity. They are meta directors. Activators are electron donating groups attached to the benzenes that have either electron density that is able to push into benzene ring or a lone pair of electrons. They are ortho–para directing.

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Chapter 18, Problem 88IP

Interpretation Introduction

Interpretation: Least reactive compound under Friedel–Craft condition has to be identified among the given compounds.

Concept Introduction:

Friedel-Crafts Alkylation: This Lewis acid-catalyzed electrophilic aromatic replacement allows the synthesis of alkylated products by means of the reaction of arenes through alkyl halides.

Electrophilic substitution reaction is a type of reaction in which a particular group or atom in a compound is replaced by electrophile. An electrophile is a species that is deficient of electrons

Deactivators are electron withdrawing groups attached to the benzenes that have either positive charge or an atom with high electronegativity. They are meta directors.

Activators are electron donating groups attached to the benzenes that have either electron density that is able to push into benzene ring or a lone pair of electrons. They are ortho–para directing.

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