Chapter 18, Problem 35P

Interpretation Introduction

Interpretation:

The reaction route required to convert the given initial product to the final product is to be provided.

Concept Introduction:

▸ LDA is lithium disopyramide. It is a strong base.

▸ In ${\text{S}}_{\text{N}}2$ reaction, one bond is broken and one bond is formed. In ${\text{S}}_{\text{N}}2$ reaction, the nucleophile attacks the less hindered carbon.

▸ Sodium hydride is used to generate the enolate ions.