Restriction mapping is technically easy, high throughput, high resolution and technically easy mapping of small DNA molecules, on the other hand FISH allow low resolution mapping of the enormous DNA molecule. STS is Sequence tagged site mapping that emerge as a powerful alternative which combines the best of mapping through FISH and best of restriction mapping.

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Chapter 18, Problem 2U

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Restriction mapping is technically easy, high throughput, high resolution and technically easy mapping of small DNA molecules, on the other hand FISH allow low resolution mapping of the enormous DNA molecule. STS is Sequence tagged site mapping that emerge as a powerful alternative which combines the best of mapping through FISH and best of restriction mapping.

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