Chapter 18, Problem 22CONQ

Summary Introduction

To review:

The role of Vpr protein in the integration of HIV DNA(human immunodeficiency virus deoxyribonucleic acid).

Introduction:

Host recognizes viral ribonucleic acid (RNA) by the tRNA(transfer RNA), which binds on virus primary binding site (PBS). For DNA synthesis 3’end of tRNA acts as a primer. Synthesis of DNA first starts from the 5’ repeats and the unique sequence at 5’ end with the help of reverse trancriptase.