Chapter 18, Problem 19PDQ

Summary Introduction

To review:

The way in which comparative genomics aid in the identification of genes responsible for a complex human disease like hypertension. Also, justify as to how comparisons of rat and human candidate loci to those in the mouse may help validate the studies.

Introduction:

Comparative genomics is a field which has many applications in research. Discovery of genes and model organisms are developed using comparative genomics. Hypertension (high blood pressure) is a condition where blood force is high enough against artery walls that it may eventually lead to health problems like heart diseases.