Compare and contrast the roles of a corepressor and an inducer in negative regulation of an operon.

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Answer 1

Textbook Question

Chapter 18, Problem 18.1CR

Compare and contrast the roles of a corepressor and an inducer in negative regulation of an operon.

Expert Solution & Answer

Summary Introduction

To compare: The functions of a corepressor and an inducer in negative regulation of an operon.

Introduction: Gene regulation is the process through which the cells control the expression of genes. It controls genes that are expressed to form a specific functional protein depending on the cell type. There are mechanisms that control gene expression at different levels.

Explanation of Solution

Operon contains coding DNA sequences, regulatory DNA sequences, and the regulatory proteins. Regulatory proteins act as both activators (TURN ON) and repressors (TURN OFF) of genes.

The similarities between corepressor and an inducer in negative regulation of an operon are as follows:

Both are small molecules that bind to the repressor protein present in an operon, causing the repressor to change its shape.

The differences between the roles of a corepressor and an inducer in negative regulation of an operon are as follows:

Characteristics

Corepressor

Inducer

Role in negative regulation of an operon

A corepressor binds to the repressor protein, activates it to bind to the operator, and thereby inhibits transcription.

For example, tryptophan acts as a corepressor in a trp operon.

The binding of an inducer to the repressor protein makes it inactive and allows transcription of operon genes.

For example, allolactose acts as an inducer in lac operon and binds to the lac repressor; hence, it cannot bind to the operator.

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Answer 2

Textbook Question

Chapter 18, Problem 18.1CR

Compare and contrast the roles of a corepressor and an inducer in negative regulation of an operon.

Expert Solution & Answer

Summary Introduction

To compare: The functions of a corepressor and an inducer in negative regulation of an operon.

Introduction: Gene regulation is the process through which the cells control the expression of genes. It controls genes that are expressed to form a specific functional protein depending on the cell type. There are mechanisms that control gene expression at different levels.

Explanation of Solution

Operon contains coding DNA sequences, regulatory DNA sequences, and the regulatory proteins. Regulatory proteins act as both activators (TURN ON) and repressors (TURN OFF) of genes.

The similarities between corepressor and an inducer in negative regulation of an operon are as follows:

Both are small molecules that bind to the repressor protein present in an operon, causing the repressor to change its shape.

The differences between the roles of a corepressor and an inducer in negative regulation of an operon are as follows:

Characteristics

Corepressor

Inducer

Role in negative regulation of an operon

A corepressor binds to the repressor protein, activates it to bind to the operator, and thereby inhibits transcription.

For example, tryptophan acts as a corepressor in a trp operon.

The binding of an inducer to the repressor protein makes it inactive and allows transcription of operon genes.

For example, allolactose acts as an inducer in lac operon and binds to the lac repressor; hence, it cannot bind to the operator.

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Answer 3

Textbook Question

Chapter 18, Problem 18.1CR

Compare and contrast the roles of a corepressor and an inducer in negative regulation of an operon.

Expert Solution & Answer

Summary Introduction

To compare: The functions of a corepressor and an inducer in negative regulation of an operon.

Introduction: Gene regulation is the process through which the cells control the expression of genes. It controls genes that are expressed to form a specific functional protein depending on the cell type. There are mechanisms that control gene expression at different levels.

Explanation of Solution

Operon contains coding DNA sequences, regulatory DNA sequences, and the regulatory proteins. Regulatory proteins act as both activators (TURN ON) and repressors (TURN OFF) of genes.

The similarities between corepressor and an inducer in negative regulation of an operon are as follows:

Both are small molecules that bind to the repressor protein present in an operon, causing the repressor to change its shape.

The differences between the roles of a corepressor and an inducer in negative regulation of an operon are as follows:

Characteristics

Corepressor

Inducer

Role in negative regulation of an operon

A corepressor binds to the repressor protein, activates it to bind to the operator, and thereby inhibits transcription.

For example, tryptophan acts as a corepressor in a trp operon.

The binding of an inducer to the repressor protein makes it inactive and allows transcription of operon genes.

For example, allolactose acts as an inducer in lac operon and binds to the lac repressor; hence, it cannot bind to the operator.

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Answer 4

Textbook Question

Chapter 18, Problem 18.1CR

Compare and contrast the roles of a corepressor and an inducer in negative regulation of an operon.

Expert Solution & Answer

Summary Introduction

To compare: The functions of a corepressor and an inducer in negative regulation of an operon.

Introduction: Gene regulation is the process through which the cells control the expression of genes. It controls genes that are expressed to form a specific functional protein depending on the cell type. There are mechanisms that control gene expression at different levels.

Explanation of Solution

Operon contains coding DNA sequences, regulatory DNA sequences, and the regulatory proteins. Regulatory proteins act as both activators (TURN ON) and repressors (TURN OFF) of genes.

The similarities between corepressor and an inducer in negative regulation of an operon are as follows:

Both are small molecules that bind to the repressor protein present in an operon, causing the repressor to change its shape.

The differences between the roles of a corepressor and an inducer in negative regulation of an operon are as follows:

Characteristics

Corepressor

Inducer

Role in negative regulation of an operon

A corepressor binds to the repressor protein, activates it to bind to the operator, and thereby inhibits transcription.

For example, tryptophan acts as a corepressor in a trp operon.

The binding of an inducer to the repressor protein makes it inactive and allows transcription of operon genes.

For example, allolactose acts as an inducer in lac operon and binds to the lac repressor; hence, it cannot bind to the operator.

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Answer 5

Textbook Question

Answer 6

Textbook Question

Answer 7

Expert Solution & Answer

Summary Introduction

To compare: The functions of a corepressor and an inducer in negative regulation of an operon.

Introduction: Gene regulation is the process through which the cells control the expression of genes. It controls genes that are expressed to form a specific functional protein depending on the cell type. There are mechanisms that control gene expression at different levels.

Explanation of Solution

Operon contains coding DNA sequences, regulatory DNA sequences, and the regulatory proteins. Regulatory proteins act as both activators (TURN ON) and repressors (TURN OFF) of genes.

The similarities between corepressor and an inducer in negative regulation of an operon are as follows:

Both are small molecules that bind to the repressor protein present in an operon, causing the repressor to change its shape.

The differences between the roles of a corepressor and an inducer in negative regulation of an operon are as follows:

Characteristics

Corepressor

Inducer

Role in negative regulation of an operon

A corepressor binds to the repressor protein, activates it to bind to the operator, and thereby inhibits transcription.

For example, tryptophan acts as a corepressor in a trp operon.

The binding of an inducer to the repressor protein makes it inactive and allows transcription of operon genes.

For example, allolactose acts as an inducer in lac operon and binds to the lac repressor; hence, it cannot bind to the operator.

Answer 8

Expert Solution & Answer

Summary Introduction

To compare: The functions of a corepressor and an inducer in negative regulation of an operon.

Introduction: Gene regulation is the process through which the cells control the expression of genes. It controls genes that are expressed to form a specific functional protein depending on the cell type. There are mechanisms that control gene expression at different levels.

Explanation of Solution

Operon contains coding DNA sequences, regulatory DNA sequences, and the regulatory proteins. Regulatory proteins act as both activators (TURN ON) and repressors (TURN OFF) of genes.

The similarities between corepressor and an inducer in negative regulation of an operon are as follows:

Both are small molecules that bind to the repressor protein present in an operon, causing the repressor to change its shape.

The differences between the roles of a corepressor and an inducer in negative regulation of an operon are as follows:

Characteristics

Corepressor

Inducer

Role in negative regulation of an operon

A corepressor binds to the repressor protein, activates it to bind to the operator, and thereby inhibits transcription.

For example, tryptophan acts as a corepressor in a trp operon.

The binding of an inducer to the repressor protein makes it inactive and allows transcription of operon genes.

For example, allolactose acts as an inducer in lac operon and binds to the lac repressor; hence, it cannot bind to the operator.

Answer 9

Expert Solution & Answer

Answer 10

Expert Solution & Answer

Answer 11

Summary Introduction

To compare: The functions of a corepressor and an inducer in negative regulation of an operon.

Introduction: Gene regulation is the process through which the cells control the expression of genes. It controls genes that are expressed to form a specific functional protein depending on the cell type. There are mechanisms that control gene expression at different levels.

Answer 12

Explanation of Solution

Operon contains coding DNA sequences, regulatory DNA sequences, and the regulatory proteins. Regulatory proteins act as both activators (TURN ON) and repressors (TURN OFF) of genes.

The similarities between corepressor and an inducer in negative regulation of an operon are as follows:

Both are small molecules that bind to the repressor protein present in an operon, causing the repressor to change its shape.

The differences between the roles of a corepressor and an inducer in negative regulation of an operon are as follows:

Characteristics

Corepressor

Inducer

Role in negative regulation of an operon

A corepressor binds to the repressor protein, activates it to bind to the operator, and thereby inhibits transcription.

For example, tryptophan acts as a corepressor in a trp operon.

The binding of an inducer to the repressor protein makes it inactive and allows transcription of operon genes.

For example, allolactose acts as an inducer in lac operon and binds to the lac repressor; hence, it cannot bind to the operator.

Answer 13

Ch. 18.1 - How does binding of the trp corepressor to the trp...Ch. 18.1 - Describe the binding of RNA Polymerase,...Ch. 18.1 - WHAT IF? A certain mutation in E. coli changes...Ch. 18.2 - In general, what are the effects of histone...Ch. 18.2 - Compare the roles of general and specific...Ch. 18.2 - WHAT IF? Suppose you compared the nucleotide...Ch. 18.2 - Once mRNA encoding a particular protein reaches...Ch. 18.3 - Compare miRNAs and siRNAs, including their...Ch. 18.3 - WH AT IF? Suppose the mRNA being degraded in...Ch. 18.4 - MAKE CONNECTIONS As you learned in Chapter 12,...

Compare and contrast the roles of a corepressor and an inducer in negative regulation of an operon.

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